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公开(公告)号:US11654203B2
公开(公告)日:2023-05-23
申请号:US17079691
申请日:2020-10-26
CPC分类号: A61K49/14 , A61K47/54 , A61K49/106 , C12N9/88 , C12Y402/01001
摘要: Disclosed herein are a dual-targeted carbonic anhydrase IX complex, a contrast agent comprising the same, and a synthesizing method thereof. The dual-targeted carbonic anhydrase IX complex includes a carbonic anhydrase IX (CA9) binding peptide, a sulfonamide derivative, and a metal chelating agent. The dual-targeted carbonic anhydrase IX complex has potential for use as a molecular nuclear drug.
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公开(公告)号:US20230133962A1
公开(公告)日:2023-05-04
申请号:US17683425
申请日:2022-03-01
发明人: SHANG-EN LIU , TIEN-HSIANG HSUEH , MIN-CHUAN WANG
IPC分类号: H01M10/0565 , H01M10/058
摘要: A composite gel polymer electrolyte lithium battery structure includes a positive electrode, a negative electrode and an electrolyte film component. The electrolyte film component, disposed between the positive electrode and the negative electrode, includes a separator and at least one electrolyte film. The at least one electrolyte film is at least consisted of sulfolane and/or propylene carbonate (PC), a lithium salt material, a solid-state polymer material and fire-retardant additives. In addition, a method for fabricating the composite gel polymer electrolyte lithium battery structure is also provided.
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公开(公告)号:US20230036752A1
公开(公告)日:2023-02-02
申请号:US17388161
申请日:2021-07-29
发明人: Chin-Chi CHEN , Ming-Chen YUAN
IPC分类号: G01T1/185
摘要: A pressure-regulating large-area windowless airflow proportional counter is provided, which includes a chamber, a metal tray, a side cover, a gas cylinder, and a voltage input and signal output terminal. The chamber has a side opening. A large-area source is placed on the metal tray and the metal tray is moved into or out of the chamber via the side opening. The side cover is fixed to the side opening by an O-ring via a locking device to form an airtight structure. The gas cylinder is used to supply a dedicated gas into the chamber. The voltage-input/signal-output terminal is used to supply voltage to an anode wire net. The free electrons generated by the large-area source due to the free phenomenon are collected by the anode wire net, and outputted to a voltage signal processing module through the voltage-input/signal-output terminal for analysis of pulse height or pulse count.
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公开(公告)号:US11466002B2
公开(公告)日:2022-10-11
申请号:US17225269
申请日:2021-04-08
发明人: Ching Yun Lee , Yu Chang
IPC分类号: C07D451/02 , C07B49/00
摘要: This invention discloses method for preparing a non-radioactive standard β-CFT. Using cocaine hydrochloride as the starting material, and after a series of hydrolysis, dehydration, esterification and bonding reactions, a non-radioactive standard (2β-Carbomethoxy-3β-(4-fluoropenyl) tropane) is prepared. Furthermore, this preparation method has fewer steps, is easy to operate, and the purity of the product is as high as 97.97%. Therefore, the method for preparing a non-radioactive standard β-CFT can promote the development of positron imaging in the diagnosis of Parkinson's disease.
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公开(公告)号:US20220085389A1
公开(公告)日:2022-03-17
申请号:US17019451
申请日:2020-09-14
发明人: Ning-Yih Hsu , Hung-Hsien Ku , Qiao-Ya Chen
IPC分类号: H01M8/0228 , H01M8/0258 , H01M8/1004
摘要: A method is provided to fabricate electrode used in super-thin flow-battery. A semi-finished cured film is prepared though colloid-mixing, impregnating, and baking. The film is pressed with different materials for fabricating various types of polar plate according to applications. Thus, a thin electrode is fabricated to contain a supporting member with thickness controllable. The electrode obtains excellent resistance to the permeation of vanadium ions; vertical-penetration volume resistance is controlled by adjusting the blending ratio of carbonaceous matter; and the demand of conductivity is met. Besides, the film is prepared to obtain a bipolar plate, a copper-containing current-collecting end plate, or other electrode material like carbon felt, carbon paper, etc. to be combined into an integrated electrode mold. Consequently, different products are obtained with different materials, where the fabrication is simple without using a high-temperature carbonization device and the component cost of flow battery is effectively reduced.
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公开(公告)号:US11260345B2
公开(公告)日:2022-03-01
申请号:US16709960
申请日:2019-12-11
发明人: Heng Yi Li , Tsair-Fuh Huang , Sheng-Fu Yang , Po-Hsiu Kuo , Yu-Ren Chen , How-Ming Lee , To-Mei Wang
摘要: A desiccant wheel is provided to be rotatable. Through the body of the wheel or a surface adsorbent, water vapor in humid air flow is adsorbed. By passing a high-temperature air flow through the wheel, the body or surface coating is regenerated with moisture removed. Along a cross-section radial, the wheel is divided into different areas. The body has three-dimensionally inter-connected pores. The pores can be of different types. The wheel is a complete concentric cylinder or a concentric cylinder comprising equal or unequal sectors. The equal or unequal sectors are separated with each other. The wheel can rotate at a fixed speed for continually repeating a process of adsorbing, transiting, and regenerating. Thereby, drying can be carried out without causing physical or chemical change to heat-sensitive material, which also improves drying efficiency, reduces size, lowers power consumption, and helps in carbon reduction for industry.
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公开(公告)号:US11258263B1
公开(公告)日:2022-02-22
申请号:US17190562
申请日:2021-03-03
发明人: Fang-Tzu Chuang , Chen-Min Chan , Ruey-Yi Lee
IPC分类号: H02J3/38 , H02J3/32 , H01M8/24 , H01M8/04828 , H02J3/00
摘要: An apparatus of solid oxide fuel cells (SOFC) is provided. The SOFCs generate power and are grid-tied. The apparatus comprises a power-generating side; and a grid-connecting side using an elementary household power management. The apparatus solves problems like low voltage, high current, voltage oscillation, voltage dips, long generator-starting time, etc. The apparatus is not only used as a stable power supply (base load), but also helps adjust the regional peak electricity demands. The features include the following: 1. A grid is tied, where output power does not pass through a direct-current boost converter and, thus, has no loss from it. 2. Injures, including voltage oscillation and sudden unloading after dumping, are reduced for avoiding further damages to cell sheets. 3. With the coordination of elementary power management and the integration of grid, the limitation of long-awaiting generator-starting time is crossed out and convenience of immediate power use is achieved.
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公开(公告)号:US11247947B2
公开(公告)日:2022-02-15
申请号:US17140246
申请日:2021-01-04
发明人: Yean-Hung Tu , Li-Yuan Huang , Jenn-Tzong Chen , Tsai-Yueh Luo , Shiou-Shiow Farn , Wuu-Jyh Lin
IPC分类号: C07B63/00 , B01J20/284 , C07B59/00
摘要: A method is provided to purify [F-18]FEONM under a high pressure. The synthesis processes of [F-18]FEONM are integrated. An isolation process of non-toxic radio-high performance liquid chromatography (radio-HPLC) is used to purify the crude product. The method integrates a convention [F-18]FDG synthesizer and a novel radio-HPLC system together in a heat chamber. After radiofluorinating the precursor, the reaction product is purified with an alumina solid-phase column in advance to obtain the crude product while fluorine-18 is removed. Then, diphenyl semipreparative HPLC column is used for a final purification. A non-toxic solvent is used for mobile-phase eluting to remove the unreacted precursor and the phase-transfer solvent. The radiofluorination has a reaction yield about 50 percent (%). The method has an uncorrected radiochemical yield of 10˜20%. Both of the radio-HPLC and the radio-thin layer chromatography (radio-TLC) have radiochemical purity higher than 95%.
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公开(公告)号:US11081717B2
公开(公告)日:2021-08-03
申请号:US16591740
申请日:2019-10-03
发明人: Ning-Yih Hsu , Chien-Hong Lin , Han-Wen Chou , Chin-Lung Hsieh , Yi-Hsin Hu , Yu-De Zhuang , Yun-Shan Tsai , Qiao-ya Chen
IPC分类号: H01M8/242 , H01M8/0221 , H01M8/0226 , H01M8/0228 , H01M8/0247 , H01M8/1023 , H01M8/248 , H01M8/18
摘要: A storage module of distributed flow battery is provided. An electrochemical reaction is processed with the positive and negative electrolytes to produce and/or discharge direct current and further output the positive and negative electrolytes after the reaction. The module comprises two end plates; two frames disposed between the two end plates; two current collectors disposed between the two frames; two complex cast polar plates disposed between the two current collectors; two electrodes disposed between the two complex cast polar plates; a membrane disposed between the two electrodes; and three gaskets. Therein, two of the gaskets are set to sandwich and enclose one of the two complex cast polar plates; and the other one of the gaskets is set between the other one of the two complex cast polar plates and an adjacent one of the current collectors.
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公开(公告)号:US11078144B2
公开(公告)日:2021-08-03
申请号:US16662308
申请日:2019-10-24
发明人: Kun-Liang Lin , Ping-Yen Wang , Mei-Hui Wang
IPC分类号: C07C37/055 , C07C67/40 , C07C67/293 , C07C67/29 , C07C37/50 , C07C67/287 , C07C41/30
摘要: Disclosed herein is a process for chemically synthesizing of hydroquinone derivatives, especially for hydroquinone derivatives with heptadecatrienyl side chain, which is synthesized via a Wittig reaction of 2-(10′-oxononyl)-1,4-diacetoxyl benzene and (3E, 5Z)-3,5-heptadien-1-triphenylphosphonium iodide and then deacetylation. In addition, the product is solid powder.
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