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公开(公告)号:US20210183521A1
公开(公告)日:2021-06-17
申请号:US17115966
申请日:2020-12-09
Inventor: Hyeon-Min BAE , Seokhwan OH , Gibbeum LEE , Myeong Gee KIM
Abstract: The method of operating an image device comprises receiving an input of virtual tissues modeled with an arbitrary shape and a quantitative feature, simulating a TOF change or a signal strength change of ultrasound data having penetrated the virtual tissues modeled with a speed-of-sound distribution or an attenuation coefficient distribution in a first and in a second direction, and creating an image pair representing the TOF change or the signal strength change, creating a speed-of-sound distribution image or an attenuation coefficient distribution image of each of the virtual tissues as a ground truth of an image pair created in the corresponding virtual tissue, and training a first neural network that reconstruct the speed-of-sound distribution image from an input image pair or training a second neural network that reconstructs the attenuation coefficient distribution image from the input image pair.
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公开(公告)号:US20210177380A1
公开(公告)日:2021-06-17
申请号:US17115939
申请日:2020-12-09
Inventor: Hyeon-Min Bae , Myeong Gee Kim , Gibbeum Lee , Seokhwan Oh , Youngmin Kim
Abstract: A method of operating an image device operated by at least one processor is provided. The method of operating an image device comprises generating beamformed RF-mode images including phase shift information for each incident angle by using multi-angle ultrasound-echo data, generating phase shift maps representing a displacement of speckle pattern between adjacent beamformed RF-mode images, and obtaining a speed-of-sound distribution image corresponding to the phase shift maps by using a deep neural network which is trained to reconstruct speed-of-sound distribution of a tissue from training phase shift maps.
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公开(公告)号:US11038480B2
公开(公告)日:2021-06-15
申请号:US16791728
申请日:2020-02-14
Inventor: Hyeokki Hong , Ji-Hun Lee , Gyu-Hyeong Cho , Cheheung Kim , Hyunwook Kang
Abstract: An amplifier includes: a first input transistor connected to a first input, a first output, and a power source or a ground, a second input transistor connected to a second input, a second output, and the power source or the ground; a first replica transistor connected to the first input, a detection node, and the power source or the ground; a second replica transistor connected to the second input, the detection node, and the power source or the ground; and a bias transistor connected to a bias voltage, the detection node, and the power source or the ground.
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公开(公告)号:US20210173923A1
公开(公告)日:2021-06-10
申请号:US16760679
申请日:2018-11-07
Inventor: Dong Uk KIM , Byung Hoon KANG , Seung Hyun HA , Dae Hee JANG , Jin Soo JANG , Seok HONG
IPC: G06F21/55 , G06F9/48 , G06F21/57 , G06F21/62 , G06F12/0831
Abstract: An electronic device is disclosed. An electronic device comprises: a first memory in which an operating system and an application program executed on the operating system are stored; a second memory; a processor for loading at least some codes among codes corresponding to an application program from the first memory to the second memory, and when access information of the codes loaded in the second memory is received from a kernel of an operating system, accessing an area in which the loaded codes are stored, on the basis of the received information and executing the application program; and a snoop for monitoring access to an area in which a preset code, the access of which has been limited, from among codes loaded in the second memory is stored.
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305.
公开(公告)号:US11032009B1
公开(公告)日:2021-06-08
申请号:US16937506
申请日:2020-07-23
Inventor: Hojae Lee , Sangrim Lee , Kyungmin Woo , Hoon Kim
Abstract: Disclosed herein is a method of transmitting a signal of a user equipment (UE) in a wireless communication system. The method includes generating an optical signal related to data transmission, combining an electrical signal for the data with the optical signal, and transmitting a combined signal.
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公开(公告)号:US11029381B2
公开(公告)日:2021-06-08
申请号:US16246598
申请日:2019-01-14
Inventor: Sung-Hong Park , Ki-Hwan Kim
IPC: G01R33/561 , G06N20/00 , G01R33/565 , G06N3/08 , G01R33/48 , G01R33/56 , G06N3/04
Abstract: Provided is an MRI image generation method including: acquiring first phase encoding lines obtained by undersampling along a first direction using an MRI device; acquiring second phase encoding lines obtained by undersampling in a second direction different from the first direction using the MRI device; generating a first MRI image based on the first phase encoding lines and the second phase encoding lines; and generating a second MRI image different from the first MRI image based on the first phase encoding lines and the second phase encoding lines.
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307.
公开(公告)号:US20210163554A1
公开(公告)日:2021-06-03
申请号:US17110924
申请日:2020-12-03
Inventor: Jin Woo KIM , Eun Jung LEE
IPC: C07K14/47
Abstract: Disclosed is a method for regulating the extracellular secretion ability of a homeoprotein and a homeoprotein variant having regulated extracellular secretion ability using the same, and more particularly, a method for increasing or decreasing the extracellular secretion ability through the increase or decrease in hydrophobicity of an amino acid sequence among homeodomain external amino acid sequences, or a homeoprotein whose extracellular secretion ability is increased or decreased through the increase or decrease in hydrophobicity of the homeodomain external amino acid sequence.
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公开(公告)号:US20210155634A1
公开(公告)日:2021-05-27
申请号:US16641604
申请日:2018-08-24
Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY , KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY , KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , CURACLE CO., LTD.
Inventor: Jin Hee Ahn , Hail Kim , Jaemyoung Suh , In-Kyu Lee , Kwang-eun Kim , Kun-Young Park , Eun Jung Bae , Ko Eun Shong , Suvarna Haus-habhau Pagire , Ajin Lim , Jae-Han Jeon , Haushabhau Shivaji Pagire , Haiying Zhang , Myung-Hwa Kim , Jung-In Pyo
IPC: C07D495/04 , C07D487/04 , C07D403/12 , C07D403/14 , C07D271/06 , C07D231/12 , C07D401/14 , C07D401/12 , C07D239/47 , C07D405/12 , C07D405/14 , C07D403/08 , A61P35/00 , A61P1/00
Abstract: The present invention relates to a novel tryptophan hydroxylase inhibitor and a pharmaceutical composition including same, wherein the novel tryptophan hydroxylase inhibitor has an excellent inhibitory effect on TPH1, and thus can be usefully used for the prevention or treatment of disorders, such as metabolic disorders, cancer, digestive or cardiovascular system disorders, related to TPH1 activity. In particular, the novel tryptophan hydroxylase inhibitor has an excellent treatment effect on inflammatory bowel disorders, and thus can be usefully used for the treatment of inflammatory bowel disorder.
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公开(公告)号:US20210154650A1
公开(公告)日:2021-05-27
申请号:US17165636
申请日:2021-02-02
Inventor: YUNHO LEE , Changho Yoo , Jonghoon Choi
Abstract: Disclosed are a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other, and exhibiting high reactivity and stability during a variety of bonding activation reactions. T-shaped complexes can be prepared from acriPNP(4,5-bis(diisopropylphosphino)-2,7,9,9-tetramethyl-9H-acridin-10-ide), which is a pincer-type PNP ligand having an acridane structure, and metal complexes, which can be structurally rigid and thus exhibit excellent reactivity and stability based on minimized structural change thereof, can be prepared by introducing an acridane structure into the backbone thereof. The PNP ligand is structurally stable and has novel chemical properties, as compared to conventional similar ligands, and thus can be utilized in a wide range of catalytic reactions and material chemistry.
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公开(公告)号:US11010524B2
公开(公告)日:2021-05-18
申请号:US15949268
申请日:2018-04-10
Inventor: Mincheol Shin , Woo Jin Jeong , Jaehyun Lee
IPC: G06F30/367 , G06F119/06
Abstract: Disclosed is a method for simulating characteristics of a semiconductor device. An overlap matrix and a Hamiltonian representing atomic interaction energy information of a target semiconductor device are extracted by using a density functional theory (DFT), and Bloch states for corresponding energies are calculated based on the Hamiltonian, the overlap matrix, and energy-k relation within an effective energy region. A first reduced Hamiltonian and a first reduced overlap matrix having a reduced matrix size are obtained by applying the Hamiltonian and the overlap matrix to a transformation matrix that is obtained by orthonormalizing a matrix representing the Bloch states. A final transformation matrix and a final energy band structure where all unphysical branches, which are energy bands not corresponding to a first energy band structure in a second energy band structure, are removed within the effective energy region are calculated.
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