公开(公告)号：US20150309144A1

公开(公告)日：2015-10-29

申请号：US14272756

申请日：2014-05-08

Applicant: General Electric Company

Inventor： Christopher Judson Hardy ,  Anja Christina Sophie Brau ,  Ek Tsoon Tan

IPC: G01R33/563 ,  G01R33/56 ,  G01R33/341 ,  G01R33/385 ,  G01R33/58 ,  G01R33/30

CPC classification number: G01R33/56316 ,  G01R33/5607

Abstract: A system and method of self-calibrated correction for residual phase in phase-contrast magnetic resonance (PCMR) imaging data. The method includes receiving PCMR image data from an MR scanner system, segmenting static tissue from non-static cardiovascular elements of the image data, calculating a non-linear fitted-phase basis function, the non-linear fitted-phase basis function based on system artifacts of the PCMR system, adding the non-linear fitted-phase basis function to linear fit terms, and subtracting the result of the adding step from the PCMR imaging data. The system includes a PCMR scanning apparatus configured to provide PCMR image data, a scanner control circuit configured to control the scanning apparatus during image acquisition, the scanner control circuitry in communication with a control processor, the control processor configured to execute computer-readable instructions that cause the control processor to perform the method. A non-transitory computer-readable medium is also disclosed.

Abstract translation: 相位对比磁共振（PCMR）成像数据中残留相自校正校正的系统和方法。 该方法包括从MR扫描器系统接收PCMR图像数据，从图像数据的非静态心血管元件分割静态组织，计算非线性拟合相位基函数，基于系统的非线性拟合相位函数 PCMR系统的伪像，将非线性拟合相位基函数加到线性拟合项，并从PCMR成像数据中减去加法步骤的结果。 该系统包括配置成提供PCMR图像数据的PCMR扫描装置，被配置为在图像采集期间控制扫描装置的扫描仪控制电路，与控制处理器通信的扫描仪控制电路，该控制处理器被配置为执行计算机可读指令， 使控制处理器执行该方法。 还公开了一种非暂时的计算机可读介质。

公开(公告)号：US20150115955A1

公开(公告)日：2015-04-30

申请号：US14067701

申请日：2013-10-30

Applicant: General Electric Company

Inventor： Seung-Kyun Lee ,  Christopher Judson Hardy ,  Ek Tsoon Tan

IPC: G01R33/561

CPC classification number: G01R33/561 ,  G01R33/4835 ,  G01R33/5611

Abstract: Magnetic resonance imaging systems and methods are provided. A method includes applying a slice selection gradient perpendicular to a desired slice plane and applying, substantially simultaneously with the slice selection gradient, a radiofrequency nuclear magnetic resonance excitation pulse having a bandwidth corresponding to the desired slice plane and a frequency corresponding to the frequency of protons present in the desired slice plane. The method also includes applying, during an encoding period and in a first direction, a phase encoding gradient having a phase encoding portion and a shearing portion and applying, during the readout period and in a second direction perpendicular to the first direction, a frequency encoding gradient having a portion having substantially the same shape as the shearing portion of the phase encoding gradient.

Abstract translation: 提供磁共振成像系统和方法。 一种方法包括应用垂直于期望切片平面的切片选择梯度并且基本上与切片选择梯度一起施加具有对应于期望切片平面的带宽和对应于质子频率的频率的射频核磁共振激励脉冲 存在于期望的切片平面中。 该方法还包括在编码周期期间和在第一方向上应用具有相位编码部分和剪切部分的相位编码梯度，并且在读出期间和垂直于第一方向的第二方向上应用频率编码 梯度具有与相位编码梯度的剪切部分基本上相同形状的部分。

公开(公告)号：US10324154B2

公开(公告)日：2019-06-18

申请号：US14711650

申请日：2015-05-13

Applicant: General Electric Company

Inventor： Jonathan Immanuel Sperl ,  Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan

IPC: G01R33/56 ,  G01R33/563

Abstract: A magnetic resonance imaging method includes generating spatially resolved fiber orientation distributions (FODs) from magnetic resonance signals acquired from a patient tissue using a plurality of diffusion encodings, each acquired magnetic resonance signal corresponding to one of the diffusion encodings and being representative of a three-dimensional distribution of displacement of magnetic spins of gyromagnetic nuclei present in each imaging voxel. Generating the spatially resolved FODs includes performing generalized spherical deconvolution using the acquired magnetic resonance signals and a modeled tissue response matrix (TRM) to reconstruct the spatially resolved FODs. The method also includes using the spatially resolved FODs to generate a representation of fibrous tissue within the patient tissue.

公开(公告)号：US20190004132A1

公开(公告)日：2019-01-03

申请号：US15637708

申请日：2017-06-29

Applicant: General Electric Company

Inventor： Ek Tsoon Tan ,  Giang-Chau Ngo ,  Christopher Judson Hardy ,  Thomas Kwok-Fah Foo

IPC: G01R33/48 ,  G01R33/56

CPC classification number: G01R33/4818 ,  G01R33/56 ,  G01R33/5611 ,  G01R33/56341

Abstract: A magnetic resonance (MR) imaging method performed by an MR imaging system includes acquiring MR data in multiple shots and multiple acquisitions (NEX), separately reconstructing the component magnitude and phase of images corresponding to the multiple shots and multiple NEX, removing the respective phase from each of the images, and combining, after removal of the respective phase, the shot images and the NEX images to produce a combined image.

公开(公告)号：US09349186B2

公开(公告)日：2016-05-24

申请号：US14177414

申请日：2014-02-11

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Xiaofeng Liu ,  John Frederick Schenck ,  Ek Tsoon Tan ,  Albert Amos Montillo

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06T7/0081 ,  G06T7/11 ,  G06T7/143 ,  G06T7/149 ,  G06T7/174 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/20076 ,  G06T2207/20128 ,  G06T2207/30016

Abstract: The system and method of the invention combines target image intensity into a maximum likelihood estimate (MLE) framework as in STAPLE to take advantage of both intensity-based segmentation and statistical label fusion based on atlas consensus and performance level, abbreviated iSTAPLE. The MLE framework is then solved using a modified expectation-maximization algorithm to simultaneously estimate the intensity profiles of structures of interest as well as the true segmentation and atlas performance level. The iSTAPLE greatly extends the use of atlases such that the target image need not have the same image contrast and intensity range as the atlas images.

Abstract translation: 本发明的系统和方法将目标图像强度与STAPLE中的最大似然估计（MLE）框架相结合，以利用基于图集共识和性能水平（简称为iSTAPLE）的基于强度的分割和统计标签融合。 然后使用修改的期望最大化算法来解决MLE框架，以同时估计感兴趣的结构的强度分布以及真实的分段和图谱性能水平。 iSTAPLE大大扩展了地图集的使用，使得目标图像不需要具有与图集图像相同的图像对比度和强度范围。

公开(公告)号：US09208587B2

公开(公告)日：2015-12-08

申请号：US14261623

申请日：2014-04-25

Applicant: General Electric Company

Inventor： Christopher Judson Hardy ,  Luca Marinelli ,  Marion Irene Menzel ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06K9/00 ,  G06T11/00 ,  G06T7/00

CPC classification number: G06T11/006 ,  G01R33/4826 ,  G01R33/5611 ,  G01R33/56341 ,  G06T7/0012 ,  G06T2207/10088 ,  G06T2207/20056

Abstract: A method of compressed sensing for multi-shell magnetic resonance imaging includes obtaining magnetic resonance imaging data, the data being sampled along multi-shell spherical coordinates, the spherical coordinates coincident with a plurality of spokes that converge at an origin, constructing a symmetric shell for each respective sampled multi-shell to create a combined set of data, performing a three-dimensional Fourier transform on the combined set of data to reconstruct an image, and de-noising the reconstructed image by iteratively applying a sparsifying transform on non-sampled data points of neighboring shells. The method can also include randomly under-sampling the imaging data to create missing data points. A system configured to implement the method and a non-transitory computer readable medium are also disclosed.

Abstract translation: 一种用于多壳磁共振成像的压缩感测方法包括：获得磁共振成像数据，所述数据沿着多壳球面坐标进行采样，所述球面坐标与在原点收敛的多个辐条重合，构成对称壳体 每个相应的采样多壳以产生一组组合数据，对该组合数据进行三维傅里叶变换以重构图像，并通过对非采样数据迭代地应用稀疏变换来对重构图像进行去噪 相邻炮弹点。 该方法还可以包括随机对取样数据进行低采样以创建丢失的数据点。 还公开了一种被配置为实现该方法的系统和一种非暂时计算机可读介质。

公开(公告)号：US20140312897A1

公开(公告)日：2014-10-23

申请号：US13866820

申请日：2013-04-19

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Ek Tsoon Tan ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Zachary William Slavens ,  Luca Marinelli ,  Robert Marc Lebel

IPC: G01R33/565

CPC classification number: G01R33/56581 ,  G01R33/56341 ,  G01R33/56572

Abstract: Systems and methods for correcting magnetic resonance (MR) data are provided. One method includes receiving the MR data and correcting errors present in the MR data due to non-uniformities in magnetic field gradients used to generate the diffusion weighted MR signals. The method also includes correcting errors present in the MR data due to concomitant gradient fields present in the magnetic field gradients by using one or more gradient terms. At least one of the gradient terms is corrected based on the correction of errors present in the MR data due to the non-uniformities in the magnetic field gradients.

Abstract translation: 提供了用于校正磁共振（MR）数据的系统和方法。 一种方法包括由于用于产生扩散加权MR信号的磁场梯度中的不均匀性，接收MR数据并校正MR数据中存在的错误。 该方法还包括通过使用一个或多个梯度项来校正存在于磁场梯度中的伴随的梯度场的MR数据中存在的误差。 由于磁场梯度中的不均匀性，基于MR数据中存在的误差的校正来校正至少一个梯度项。

公开(公告)号：US20140185894A1

公开(公告)日：2014-07-03

申请号：US13728871

申请日：2012-12-27

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Marion Irene Menzel ,  Christopher Judson Hardy ,  Kevin Franklin King ,  Luca Marinelli ,  Ek Tsoon Tan ,  Jonathan Immanuel Sperl

IPC: G06T7/00

CPC classification number: G01R33/56341

Abstract: A magnetic resonance (MR) imaging method includes acquiring MR signals having phase and magnitude at q-space locations using a diffusion sensitizing pulse sequence performed on a tissue of interest, wherein the acquired signals each include a set of complex Fourier encodings representing a three-dimensional displacement distribution of the spins in a q-space location. The signals each include information relating to coherent motion and incoherent motion in the q-space location. The method also includes determining a contribution by coherent motion to the phase of the acquired MR signals; removing the phase contribution attributable to coherent motion from the acquired MR signals to produce a complex data set for each q-space location and an image of velocity components for each q-space location; and producing a three-dimensional velocity image from the image of the velocity components.

Abstract translation: 磁共振（MR）成像方法包括使用在感兴趣的组织上执行的扩散增感脉冲序列获取在q空间位置具有相位和幅度的MR信号，其中所获取的信号各自包括一组代表三维空间的复数傅里叶编码， 在q空间位置的自旋的三维位移分布。 每个信号包括与q空间位置中的相干运动和非相干运动有关的信息。 该方法还包括通过相干运动确定所获取的MR信号的相位的贡献; 从所获取的MR信号去除归因于相干运动的相位贡献，以产生用于每个q空间位置的复数数据集和用于每个q空间位置的速度分量的图像; 并根据速度分量的图像产生三维速度图像。