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公开(公告)号:US12201809B2
公开(公告)日:2025-01-21
申请号:US17386659
申请日:2021-07-28
Applicant: AMGEN INC.
Inventor: Scott R. Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Antonio Ubach , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Ian P. Dardani , Sean M. O'connor , Danielle Feldman
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
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公开(公告)号:US11590277B2
公开(公告)日:2023-02-28
申请号:US16488120
申请日:2018-03-06
Applicant: AMGEN INC.
Inventor: Brian Stonecipher , Margaux Frances Boyaval , James Chan , Avon Kuo , Allan Lee Cameron , Maxwell Franklin Bischoff , Gregg Allen Flender
Abstract: A wearable drug delivery device includes an injector having a housing, a reservoir, a needle or cannula, a drive mechanism for urging drug product out of the reservoir, through the needle or cannula, and to a patient, and an activator mechanism disposed on a surface of the housing for activating the drive mechanism. An activation prevention mechanism is coupled to the injector housing and/or activation prevention mechanism to prevent inadvertent actuation of the activator mechanism.
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公开(公告)号:US20220218900A1
公开(公告)日:2022-07-14
申请号:US17688578
申请日:2022-03-07
Applicant: AMGEN INC.
Inventor: Scott R. Gibson , Sheldon B, Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Sean M. O'connor , Robert Decker , Gautam N. Shetty , Ryan M. Agard , Nicholas J. Ciccarelli , Daniel Davenport
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.
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公开(公告)号:USD951434S1
公开(公告)日:2022-05-10
申请号:US29758733
申请日:2020-11-18
Applicant: AMGEN INC.
Designer: Margaux Frances Boyaval , Sigrid Moeslinger , Lisa Nugent , Brian Stonecipher , Masamichi Udagawa
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公开(公告)号:USD922567S1
公开(公告)日:2021-06-15
申请号:US29748308
申请日:2020-08-28
Applicant: AMGEN INC.
Designer: Margaux Frances Boyaval , Sigrid Moeslinger , Masamichi Udagawa
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公开(公告)号:US20200316291A1
公开(公告)日:2020-10-08
申请号:US16089685
申请日:2017-04-07
Applicant: AMGEN INC.
Inventor: Scott Robert Gibson , Sheldon B. Moberg , Basel Hasan Taha , Margaux Frances Boyaval , Mark A. Destefano , Lawton Laurence , John C. Love , Ian B. Hanson , Paul F. Bente, IV , Matthew J. Clemente , Antonio Ubach , Rajan Ramaswamy , Daniel S. Codd , Scott Beaver , Kevin L. Bokelman , Ian P. Dardani , Sean M. O'connor , Danielle Feldman
Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device includes a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector defines a sterile fluid flowpath between the container and the insertion mechanism. A cannula initially disposed about the needle is included.
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公开(公告)号:US20190381238A1
公开(公告)日:2019-12-19
申请号:US16488120
申请日:2018-03-06
Applicant: AMGEN INC.
Inventor: Brian Stonecipher , Margaux Frances Boyaval , James Chan , Avon Kuo , Allan Lee Cameron , Maxwell Franklin Bischoff , Gregg Allen Flender
Abstract: A wearable drug delivery device includes an injector having a housing, a reservoir, a needle or cannula, a drive mechanism for urging drug product out of the reservoir, through the needle or cannula, and to a patient, and an activator mechanism disposed on a surface of the housing for activating the drive mechanism. An activation prevention mechanism is coupled to the injector housing and/or activation prevention mechanism to prevent inadvertent actuation of the activator mechanism.
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公开(公告)号:USD830539S1
公开(公告)日:2018-10-09
申请号:US29563102
申请日:2016-05-02
Applicant: AMGEN INC.
Designer: Margaux Frances Boyaval , Sigrid Moeslinger , Masamichi Udagawa
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公开(公告)号:USD1070072S1
公开(公告)日:2025-04-08
申请号:US29758728
申请日:2020-11-18
Applicant: AMGEN INC.
Designer: Margaux Frances Boyaval , Sigrid Moeslinger , Lisa Nugent , Brian Stonecipher , Masamichi Udagawa
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公开(公告)号:USD1065512S1
公开(公告)日:2025-03-04
申请号:US29962679
申请日:2024-09-12
Applicant: AMGEN INC.
Designer: Margaux Frances Boyaval , Sigrid Moeslinger , Masamichi Udagawa
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