公开(公告)号：US20050220910A1

公开(公告)日：2005-10-06

申请号：US10906303

申请日：2005-02-14

申请人： Pui-Kwong CHAN ,  May Sung MAK ,  Yun WANG

发明人： Pui-Kwong CHAN ,  May Sung MAK ,  Yun WANG

IPC分类号： A61K31/704 ,  A61K35/78

CPC分类号： A61K31/704 ,  A61K36/77 ,  C07H15/256 ,  C07J63/00

摘要： This invention provides compositions, methods and process of producing extracts from Xanthoceras sorbifolia. The extract comprises alkaloids, coumarins, saccharides, proteins, polysaccharides, glycosides, saponins, tannins, acid, flavonoids and others. The composition can be used for treating cancer, arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder, impotence and premature ejaculation; for preventing cerebral aging; for improving memory, cerebral functions; or for curing enuresis, frequent micturition, urinary incontinence, dementia, weak intelligence and Alzheimer's disease, autism, brain trauma, Parkinson's disease or other diseases caused by cerebral dysfunctions, and treating arthritis, rheumatism, poor circulation, arteriosclerosis, Raynaud's syndrome, angina pectoris, cardiac disorder, coronary heart disease, headache, dizziness, kidney disorder. This invention provides compounds comprising at least one sugar, a triterpene, such as Sapogenin, and at least one side chains at Carbon 21 and 22, such as Angeloyl groups. The compounds of the present have various pharmaceutical and therapeutic applications.

摘要翻译： 本发明提供了从山茱萸生产提取物的组合物，方法和方法。 提取物包括生物碱，香豆素，糖类，蛋白质，多糖，糖苷，皂苷，单宁，酸，黄酮等。 该组合物可用于治疗癌症，关节炎，风湿病，循环不良，动脉硬化，雷诺综合征，心绞痛，心脏病，冠心病，头痛，头晕，肾脏疾病，阳ence和早泄; 用于预防脑衰老; 改善记忆力，脑功能; 或用于治疗遗尿，频繁排尿，尿失禁，痴呆，弱智能和阿尔茨海默病，自闭症，脑外伤，帕金森病或由脑功能障碍引起的其他疾病，以及治疗关节炎，风湿病，循环不良，动脉硬化，雷诺综合征，心绞痛 ，心脏病，冠心病，头痛，头晕，肾脏疾病。 本发明提供了包含至少一种糖，三萜类，例如皂角蛋白原的化合物和在碳21和22的至少一个侧链如阴离子基团的化合物。 本发明的化合物具有各种药物和治疗应用。