公开(公告)号：US20220370451A1

公开(公告)日：2022-11-24

申请号：US17764658

申请日：2020-10-06

申请人： VIIV HEALTHCARE UK ( No. 5) LIMITED

发明人： Michael S. BOWSHER ,  Eric P. GILLIS ,  Kyle E. PARCELLA ,  Christiana IWUAGWU

IPC分类号： A61K31/517 ,  C07D403/14 ,  C07D471/04 ,  C07D401/14 ,  A61K31/519 ,  A61K31/5365 ,  A61K31/537 ,  A61K31/506 ,  A61K31/675 ,  A61K31/4985 ,  A61P31/18

摘要： Compounds and pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.

公开(公告)号：US20210395262A1

公开(公告)日：2021-12-23

申请号：US17284816

申请日：2019-10-22

申请人： ViiV HEALTHCARE UK (NO.5) LIMITED

发明人： Eric P. GILLIS ,  Kyle E. PARCELLA ,  Manoj PATEL ,  Christiana IWUAGWU ,  Michael S. BOWSHER ,  Alan Xiangdong WANG

IPC分类号： C07D491/107 ,  C07D403/14 ,  C07D413/14 ,  C07D498/18 ,  C07D417/14 ,  C07D498/08 ,  A61K45/06

摘要： Compounds of Formula I, including pharmaceutically acceptable salts thereof, and compositions and methods for treating human immunodeficiency virus (HIV) infection are set forth.

公开(公告)号：US20200055839A1

公开(公告)日：2020-02-20

申请号：US16465199

申请日：2018-01-02

申请人： VIIV HEALTHCARE UK (NO.5) LIMITED

发明人： Makonen BELEMA ,  Michael S. BOWSHER ,  Jeffrey A. DESKUS ,  Kyle J. EASTMAN ,  Eric P. GILLIS ,  David B. FRENNESSON ,  Christiana IWUAGWU ,  John F. KADOW ,  B. Narasimhulu NAIDU ,  Kyle E. PARCELLA ,  Kevin M. PEESE ,  Mark G. SAULNIER ,  Prasanna SIVAPRAKASAM

IPC分类号： C07D401/14 ,  C07D401/04 ,  C07D491/048 ,  C07D405/14 ,  C07D413/14 ,  A61P31/18

摘要： Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.