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11.发明授权Compounds that modulate PPARγ-type receptors and cosmetic/pharmaceutical compositions comprising said compounds 失效调节PPARγ型受体的化合物和包含所述化合物的化妆品/药物组合物公开(公告)号：US07968560B2
公开(公告)日：2011-06-28
申请号：US12585634
申请日：2009-09-21
Applicant: Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
Inventor： Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
IPC: A61K31/505 , A61K31/445 , A61K31/44 , A61K31/41 , A61K31/425 , A61K31/415 , A61K31/38 , A61K31/34 , C07D239/02 , C07D211/06 , C07D213/00 , C07D285/10 , C07D277/20 , C07D249/14 , C07D233/28 , C07D333/36 , C07D307/02
CPC classification number: C07D213/75 , C07D213/55 , C07D239/26 , C07D239/42 , C07D249/14 , C07D277/30 , C07D277/48 , C07D307/54 , C07D333/24 , C07D401/12 , C07D409/04 , C07D413/06 , C07D417/06 , C07D417/10 , C07D417/12
Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
Abstract translation: 具有以下通式（I）的新型化合物可用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）的广泛应用中，或 ，或者配制成化妆品组合物。
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公开(公告)号：US20100035988A1
公开(公告)日：2010-02-11
申请号：US12588267
申请日：2009-10-09
Applicant: Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
Inventor： Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
IPC: A61K31/24
CPC classification number: C07C275/42 , C07C2601/02 , C07C2601/08 , C07C2601/14
Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
Abstract translation: 具有以下结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物，特别是皮肤病学以及心血管疾病，免疫疾病和/或代谢相关疾病领域的药物组合物 的脂质，或者替代为化妆品组合物。
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公开(公告)号：US20100099689A1
公开(公告)日：2010-04-22
申请号：US12562665
申请日：2009-09-18
Applicant: Laurence CLARY , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
Inventor： Laurence CLARY , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
IPC: A61K31/505 , A61K31/425 , A61K31/506 , A61K31/44 , A61P17/00
CPC classification number: C07D213/75 , C07D213/55 , C07D239/26 , C07D239/42 , C07D249/14 , C07D277/30 , C07D277/48 , C07D307/54 , C07D333/24 , C07D401/12 , C07D409/04 , C07D413/06 , C07D417/06 , C07D417/10 , C07D417/12
Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
Abstract translation: 具有以下通式（I）的新型化合物可用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）的广泛应用中，或 ，或者配制成化妆品组合物。
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14.发明授权Compounds that modulate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的化合物和包含它们的化妆品/药物组合物公开(公告)号：US07625914B2
公开(公告)日：2009-12-01
申请号：US11311449
申请日：2005-12-20
Applicant: Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
Inventor： Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
IPC: A61K31/505 , A61K31/445 , A61K31/44 , A61K31/41 , A61K31/425 , A61K31/415 , A61K31/38 , A61K31/34 , C07D239/02 , C07D211/06 , C07D213/00 , C07D285/10 , C07D277/20 , C07D249/14 , C07D233/28 , C07D333/36 , C07D307/02
CPC classification number: C07D213/75 , C07D213/55 , C07D239/26 , C07D239/42 , C07D249/14 , C07D277/30 , C07D277/48 , C07D307/54 , C07D333/24 , C07D401/12 , C07D409/04 , C07D413/06 , C07D417/06 , C07D417/10 , C07D417/12
Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
Abstract translation: 具有以下通式（I）的新型化合物可用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）的广泛应用中，或 ，或者配制成化妆品组合物。
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15.发明申请Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof 审中-公开PPAR型受体的新型调节剂及其组合的美容/药物组合物公开(公告)号：US20060035969A1
公开(公告)日：2006-02-16
申请号：US11202059
申请日：2005-08-12
Applicant: Philippe Diaz , Etienne Thoreau , Isabelle Carlavan , Pascale Mauvais , Johannes Voegel
Inventor： Philippe Diaz , Etienne Thoreau , Isabelle Carlavan , Pascale Mauvais , Johannes Voegel
IPC: A61K31/24 , C07C311/45
CPC classification number: C07C323/62 , C07C2601/14
Abstract: Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.
Abstract translation: 调节PPAR-型受体的新型化合物具有以下通式（I）：并配制成适用于人或兽医学药物（在皮肤病学和心血管疾病，免疫疾病和/或与 脂质代谢），或配制成化妆品组合物。
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Patent Agency Ranking
16.发明授权Biaromatic compounds which activate PPARγ-type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效激活PPARγ型受体的双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US07626054B2
公开(公告)日：2009-12-01
申请号：US11592276
申请日：2006-11-03
Applicant: Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
Inventor： Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
IPC: C07C241/00
CPC classification number: C07C275/42 , C07C2601/02 , C07C2601/08 , C07C2601/14
Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
Abstract translation: 具有以下结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物，特别是皮肤病学以及心血管疾病，免疫疾病和/或代谢相关疾病领域的药物组合物 的脂质，或者替代为化妆品组合物。
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17.发明申请Novel biaromatic compounds which activate PPARy-type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效活化PPARγ型受体的新颖的双芳族化合物和包含它们的化妆品/药物组合物公开(公告)号：US20070112070A1
公开(公告)日：2007-05-17
申请号：US11592276
申请日：2006-11-03
Applicant: Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
Inventor： Jerome Aubert , Laurence Clary , Pascale Mauvais , Michel Rivier , Etienne Thoreau , Jean-Guy Boiteau
IPC: A61K31/24 , A61K31/195 , C07C275/42
CPC classification number: C07C275/42 , C07C2601/02 , C07C2601/08 , C07C2601/14
Abstract: Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
Abstract translation: 具有以下结构式（I）的新颖的双芳族化合物被配制成适用于人或兽医药物，特别是皮肤病学以及心血管疾病，免疫疾病和/或代谢相关疾病领域的药物组合物 的脂质，或者替代为化妆品组合物。
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18.发明申请Novel compounds that modulate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof 失效调节PPARγ型受体的新型化合物及其组合的美容/药物组合物公开(公告)号：US20060148862A1
公开(公告)日：2006-07-06
申请号：US11311449
申请日：2005-12-20
Applicant: Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
Inventor： Laurence Clary , Etienne Thoreau , Michel Rivier , Jerome Aubert , Laurent Chantalat , Johannes Voegel
IPC: A61K31/433 , A61K31/427 , A61K31/4245 , C07D417/02 , C07D413/02
CPC classification number: C07D213/75 , C07D213/55 , C07D239/26 , C07D239/42 , C07D249/14 , C07D277/30 , C07D277/48 , C07D307/54 , C07D333/24 , C07D401/12 , C07D409/04 , C07D413/06 , C07D417/06 , C07D417/10 , C07D417/12
Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
Abstract translation: 具有以下通式（I）的新型化合物可用于人或兽医学（在皮肤病学以及心血管疾病，免疫疾病和/或与脂质代谢相关的疾病领域）的广泛应用中，或 ，或者配制成化妆品组合物。
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19.发明申请Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof 审中-公开PPAR型受体的新型调节剂及其组合的美容/药物组合物公开(公告)号：US20060052627A1
公开(公告)日：2006-03-09
申请号：US11202019
申请日：2005-08-12
Applicant: Philippe Diaz , Etienne Thoreau , Isabelle Carlavan , Pascale Mauvais , Johannes Voegel
Inventor： Philippe Diaz , Etienne Thoreau , Isabelle Carlavan , Pascale Mauvais , Johannes Voegel
IPC: C07D241/02 , C07D239/02 , C07D237/02 , C07C229/40
CPC classification number: C07C323/62
Abstract: Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.
Abstract translation: 调节PPAR-型受体的新型化合物具有以下通式（I）：
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20.发明授权Heterocyclic biaryl compounds and pharmaceutical/cosmetic compositions comprised thereof 失效杂环联芳基化合物和由其组成的药物/化妆品组合物
公开(公告)号：US5905088A
公开(公告)日：1999-05-18
申请号：US886039
申请日：1997-06-30
Applicant: Philippe Diaz , Etienne Thoreau
Inventor： Philippe Diaz , Etienne Thoreau
IPC: C07D333/60 , A61K8/00 , A61K8/49 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61P17/00 , A61P27/02 , A61Q5/00 , A61Q7/00 , A61Q19/00 , C07D307/12 , C07D307/92 , C07D409/04
CPC classification number: C07D409/04 , C07D307/92 , Y02P20/55 , Y10S514/844 , Y10S514/852
Abstract: Novel pharmaceutically/cosmetically-active heterocyclic biaryl compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(h): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular and ophthalmological disorders, as well as for cosmetic applications and for the treatment of mammalian skin and hair conditions/disorders.
Abstract translation: 新的药物/化妆活性杂环联芳基化合物具有结构式（I）：其中Ar是具有式（a） - （h）之一的基团：并且可用于治疗各种各样的疾病状态，无论是否 人或兽医，例如皮肤病学，风湿性，呼吸道，心血管和眼科疾病，以及用于化妆品应用和治疗哺乳动物皮肤和毛发病症/病症。
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