公开(公告)号：US09758770B2

公开(公告)日：2017-09-12

申请号：US14807608

申请日：2015-07-23

Applicant: Samsung Electronics Co., Ltd.

Inventor： Huisub Lim ,  Sungsoo Kim ,  Jiyoon Song ,  Soyoung Lee ,  Juyoung Lee ,  Kwangmyung Cho

IPC: C12N9/12 ,  C12N15/82 ,  C12N1/19 ,  C12P7/56 ,  C07K14/39 ,  C07K14/395 ,  C12N15/81

CPC classification number: C12N9/1205 ,  C07K14/39 ,  C07K14/395 ,  C12N9/12 ,  C12N15/81 ,  C12P7/56 ,  C12Y207/11001

Abstract: Provided is an acid-resistant yeast cell that is genetically engineered to enhance activity of a radiation sensitivity complementing kinase, and a method of producing lactate by using the yeast cell.

公开(公告)号：US09758564B2

公开(公告)日：2017-09-12

申请号：US14747848

申请日：2015-06-23

Applicant: Samsung Electronics Co., Ltd.

Inventor： Juyoung Lee ,  Hyunyoung Shin ,  Changduk Kang ,  Seunghyun Lee ,  Kwangmyung Cho

IPC: C12N1/14 ,  C07K14/705 ,  C12P7/56 ,  C07K14/395

CPC classification number: C07K14/705 ,  C07K14/395 ,  C12P7/56 ,  C12Y101/01027

Abstract: Provided are an acid-resistant yeast cell with genetic modification and reduced Fps1 activity compared to that of a parent cell without the genetic modification; and a method of producing lactate by using the yeast cell.

公开(公告)号：US09663803B2

公开(公告)日：2017-05-30

申请号：US14541051

申请日：2014-11-13

Applicant: Samsung Electronics Co., Ltd.

Inventor： Juyoung Lee ,  Changduk Kang ,  Soyoung Lee ,  Youngkyoung Park ,  Jiyoon Song ,  Seunghyun Lee ,  Kwangmyung Cho

IPC: C12N9/90 ,  C12P7/56 ,  C12N15/81

CPC classification number: C12P7/56 ,  C12N15/81 ,  C12Y503/01001

Abstract: A genetically engineered yeast cell capable of producing lactate having increased TPI activity, a method of preparing the yeast cell, and a method of producing lactate by using the yeast cell.

公开(公告)号：US09562243B2

公开(公告)日：2017-02-07

申请号：US14563774

申请日：2014-12-08

Applicant: Samsung Electronics Co., Ltd.

Inventor： Youngkyoung Park ,  Changduk Kang ,  Jiyoon Song ,  Juyoung Lee ,  Seunghyun Lee ,  Kwangmyung Cho

IPC: C12P7/56 ,  C12N9/00

CPC classification number: C12P7/56 ,  C12N9/93 ,  C12Y604/01001 ,  Y02P20/52

Abstract: A yeast cell with reduced pyruvate to oxaloacetate conversion activity, and a method of producing lactate using the yeast cell.

Abstract translation: 具有降低的丙酮酸至草酰乙酸酯转化活性的酵母细胞，以及使用酵母细胞产生乳酸的方法。

公开(公告)号：US20150152447A1

公开(公告)日：2015-06-04

申请号：US14559426

申请日：2014-12-03

Applicant: Samsung Electronics Co., Ltd.

Inventor： Sungsoo Kim ,  Jiyoon Song ,  Changduk Kang ,  Juyoung Lee ,  Seunghyun Lee ,  Kwangmyung Cho

IPC: C12P7/56 ,  C12N9/04 ,  C12N15/81 ,  C12N9/02

CPC classification number: C12P7/56 ,  C12N9/0006 ,  C12N9/0008 ,  C12N15/81 ,  C12Y101/01027 ,  C12Y102/01012

Abstract: A genetically modified yeast cell comprising increased glyceraldehyde-3-phosphate dehydrogenase activity converting glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate as compared to a parent yeast cell of the same type, and reduced glycerol-3-phosphate dehydrogenase activity converting dihydroxyacetone phosphate to glycerol-3-phosphate compared to a parent yeast cell of the same type, and related compositions and methods.

Abstract translation: 与相同类型的亲本酵母细胞相比，包含增加的甘油醛-3-磷酸脱氢酶活性的甘油醛-3-磷酸脱氢酶活性将甘油醛-3-磷酸转化为1,3-二磷酸甘油酸的转基因酵母细胞，以及转化的二羟基丙酮磷酸酯的甘油-3-磷酸脱氢酶活性的降低 与相同类型的亲本酵母细胞相比，相对于甘油-3-磷酸酯，以及相关的组合物和方法。