公开(公告)号：US20130018434A1

公开(公告)日：2013-01-17

申请号：US13619055

申请日：2012-09-14

Applicant: Mark J. Zdeblick ,  Benedict James Costello ,  Jeremy Frank ,  Marc Jensen ,  Todd Thompson ,  Mohammed Z. Islam

Inventor： Mark J. Zdeblick ,  Benedict James Costello ,  Jeremy Frank ,  Marc Jensen ,  Todd Thompson ,  Mohammed Z. Islam

IPC: A61N1/375 ,  H01R43/00

CPC classification number: A61N1/05 ,  H01L21/561 ,  H01L23/3107 ,  H01L24/63 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01024 ,  H01L2924/01033 ,  H01L2924/01044 ,  H01L2924/01045 ,  H01L2924/01047 ,  H01L2924/01049 ,  H01L2924/01074 ,  H01L2924/01076 ,  H01L2924/01077 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/10253 ,  H01L2924/12042 ,  H01L2924/14 ,  H01L2924/1461 ,  H01L2924/15787 ,  Y10T29/49117 ,  H01L2924/00

Abstract: An implantable integrated circuit structure comprising a conformal thin-film sealing layer for hermetically sealing circuitry layers is provided. Also disclosed are electrode structures, leads that include the same, implantable pulse generators that include the leads, as well as systems and kits having components thereof, other implantable devices utilizing the structures, and methods of making and using the subject structures.

Abstract translation: 提供了一种包括用于密封电路层的保形薄膜密封层的可植入集成电路结构。 还公开了电极结构，包括相同的引线，包括引线的可植入脉冲发生器，以及具有其部件的系统和套件，利用该结构的其它可植入装置，以及制造和使用受试结构的方法。

公开(公告)号：US08195308B2

公开(公告)日：2012-06-05

申请号：US11794016

申请日：2005-12-22

Applicant: Jeremy Frank ,  Vladimier Gelfandbein ,  Marc Jensen ,  Mark J. Zdeblick ,  Benedict James Costello

Inventor： Jeremy Frank ,  Vladimier Gelfandbein ,  Marc Jensen ,  Mark J. Zdeblick ,  Benedict James Costello

IPC: A61N1/05

CPC classification number: A61N1/375 ,  A61N1/05 ,  A61N1/37205 ,  A61N1/3756

Abstract: Implantable hermetically sealed structures and methods for making the same. Devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems are included.

Abstract translation: 可植入的密封结构及其制造方法。 还包括包括密封结构在内的装置，系统和试剂盒以及使用这些装置和系统的方法。

公开(公告)号：US07837634B2

公开(公告)日：2010-11-23

申请号：US11368259

申请日：2006-03-03

Applicant: Benedict James Costello

Inventor： Benedict James Costello

IPC: A61B5/103 ,  A61B5/117 ,  F21V9/00 ,  G02B6/26 ,  G02B6/42

CPC classification number: A61N1/056 ,  A61N1/08 ,  A61N1/36514 ,  A61N1/36578 ,  A61N2001/0585

Abstract: Devices and methods for evaluating motion of a tissue location, such as cardiac tissue location, e.g., heart wall, are provided. Devices employed in the subject methods are fiberoptic tissue motion sensors that include a light guide having a reflective element at its distal end and a light emitter/detector at its proximal end. In embodiments of the methods, a signal obtained from reflective element stably associated with the tissue location of interest is employed to evaluate movement of the tissue location. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.

Abstract translation: 提供了用于评估组织位置的运动的装置和方法，例如心脏组织位置，例如心脏壁。 在本发明方法中使用的装置是光纤组织运动传感器，其包括在其远端具有反射元件的光导和在其近端处的光发射器/检测器。 在方法的实施例中，采用从与感兴趣的组织位置稳定相关联的反射元件获得的信号来评估组织位置的移动。 主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

公开(公告)号：US20090082645A1

公开(公告)日：2009-03-26

申请号：US12238345

申请日：2008-09-25

Applicant: Hooman Hafezi ,  Benedict James Costello ,  Timothy L. Robertson ,  Maria Casillas Holen

Inventor： Hooman Hafezi ,  Benedict James Costello ,  Timothy L. Robertson ,  Maria Casillas Holen

IPC: A61B5/07

CPC classification number: A61B5/073 ,  A61B5/0002 ,  A61B5/0028 ,  A61B5/028 ,  A61B5/14539 ,  A61B5/14546 ,  A61B2562/02 ,  A61B2562/162 ,  A61B2562/182 ,  H01Q1/2208 ,  H01Q1/273 ,  H01Q9/16 ,  H04B13/005 ,  Y10S128/902

Abstract: Virtual dipole signal amplification for in-body devices, such as implantable and ingestible devices, is provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.

Abstract translation: 提供了诸如可植入和可摄取装置的体内装置的虚拟偶极子信号放大。 本发明的体内可展开天线的方面包括配置成在放置在生物体中（例如通过摄取或植入）之后从第一配置转到第二配置的天线。 身体内装置的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。