Abstract:
The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.
Abstract:
Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.
Abstract:
Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.
Abstract:
The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.
Abstract:
Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.
Abstract:
The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.
Abstract:
The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.
Abstract:
Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.
Abstract:
The disclosure provides methods and systems for determining tissue oxygenation. An electronic device obtains a data set including a plurality of images of a tissue of interest, each resolved at a different spectral band. Spectral analysis is performed, upon image registration, at a plurality of points in a two-dimensional area of the images of the tissue. The spectral analysis including determining approximate values of oxyhemoglobin levels and deoxyhemoglobin levels at each respective point in the plurality of points. The predetermined set of eight to twelve spectral bands includes spectral bands that provide improved methods for measuring tissue oxygenation.
Abstract:
The disclosure provides computer systems, non-transitory computer-readable storage medium, and methods for determining the presence of a skin indication in a subject. In some aspects the method includes acquiring a hyperspectral imaging data set from a region of interest of a human subject using a hyperspectral imager, and applying the hyperspectral imaging data set against a classifier including a two layered media model, the two layered media model including a first layer of a modeled human tissue overlying a second layer of the modeled human tissue, where the two layered media model has been trained by application of simulated data across a set of optical and geometric properties associated with the presence or the absence of a skin indication, where the two layered media model computes tissue reflectance R from the modeled human tissue by a relationship provided herein.