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公开(公告)号：US20170132788A1
公开(公告)日：2017-05-11
申请号：US14936903
申请日：2015-11-10
Applicant: General Electric Company
Inventor： Prem Venugopal , Thomas Kwok-Fah Foo , Christopher Judson Hardy , Ek Tsoon Tan
CPC classification number: G06T7/0014 , A61B5/02007 , A61B5/022 , A61B5/026 , A61B5/0285 , A61B5/055 , A61B5/7275 , G06T7/11 , G06T7/62 , G06T2207/10088 , G06T2207/30104 , G16H30/40 , G16H50/30
Abstract: A method for determining an arterial pulse wave velocity representative of a health condition of a blood vessel includes receiving an image data set comprising a plurality of images of a subject, from an imaging modality. The method also involves determining a blood vessel region in an image from the plurality of images. The method further includes determining a plurality of cross-sectional area values of a blood vessel at a plurality of locations in the blood vessel region, corresponding to a plurality of phases of a cardiac cycle of the subject and determining a plurality of flow rate values of blood flowing in the blood vessel corresponding to the plurality of cross-sectional area values. The method also includes determining a hemodynamic model based on the plurality of cross-sectional area values and the plurality of blood flow rate values and determining the arterial pulse wave velocity based on the hemodynamic model.
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公开(公告)号：US11384640B2
公开(公告)日：2022-07-12
申请号：US16199353
申请日：2018-11-26
Applicant: General Electric Company
Inventor： Jalindar Appa Walunj , Sylvain Pierre , Prem Venugopal
Abstract: A turbine rotor blade including an airfoil that extends from a platform. The platform may include a first portion of a nominal platform contour substantially in accordance with Cartesian coordinate values of X′, Y′, and Z′ as set forth in Table II. The Cartesian coordinate values of X′, Y′, and Z′ are non-dimensional values from 0% to 100% convertible to dimensional distances by multiplying the Cartesian coordinate values of X′, Y′, and Z′ by a height of the airfoil defined along a Z′ axis. The X′ and Y′ values of the first portion are coordinate values that, when connected by smooth continuing arcs, define contour lines of the first portion of the nominal airfoil profile at each Z′ coordinate value. The contour lines may be joined smoothly with one another to form the first portion.
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Patent Agency Ranking
公开(公告)号：US20220071497A1
公开(公告)日：2022-03-10
申请号：US17422653
申请日：2020-01-16
Applicant: General Electric Company
Inventor： Prem Venugopal , Peter Michael Edic , Thomas Kwok-Fah Foo
Abstract: The present disclosure relates to the use of prior images acquired of the patient and acoustic signature from a vascular region of interest to create a patient-specific model of sound propagation from the vascular region. This model is then used to monitor the progression of disease in the vascular region of interest, using subsequently-acquired acoustic signals. In an alternate embodiment, population-based images and/or population-based acoustic signatures are used to generate predictive data when a priori patient-specific imaging information is not available and this data is used to characterize or categorize at-risk patients suspected of coronary artery disease, but without prior cardiac events.
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公开(公告)号：US10674986B2
公开(公告)日：2020-06-09
申请号：US15154360
申请日：2016-05-13
Applicant: General Electric Company
Inventor： Prem Venugopal , Jed Douglas Pack , Bruno Kristiaan Bernard De Man , Peter Michael Edic , Jiang Hsieh
Abstract: The present approach provides a non-invasive methodology for estimation of coronary flow and/or fractional flow reserve. In certain implementations, various approaches for personalizing blood flow models of the coronary vasculature are described. The described personalization approaches involve patient-specific measurements and do not assume or rely on the resting coronary flow being proportional to myocardial mass. Consequently, there are fewer limitations in using these approaches to obtain coronary flow and/or fractional flow reserve estimates non-invasively.
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公开(公告)号：US20200160509A1
公开(公告)日：2020-05-21
申请号：US16192551
申请日：2018-11-15
Applicant: General Electric Company
Inventor： Jed Douglas Pack , Peter Michael Edic , Xin Wang , Xia Li , Prem Venugopal , James Vradenburg Miller
Abstract: The present disclosure relates to training one or more neural networks for vascular vessel assessment using synthetic image data for which ground-truth data is known. In certain implementations, the synthetic image data may be based in part, or derived from, clinical image data for which ground-truth data is not known or available. Neural networks trained in this manner may be used to perform one or more of vessel segmentation, decalcification, Hounsfield unit scoring, and/or estimation of a hemodynamic parameter.
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公开(公告)号：US20170325769A1
公开(公告)日：2017-11-16
申请号：US15154360
申请日：2016-05-13
Applicant: General Electric Company
Inventor： Prem Venugopal , Jed Douglas Pack , Bruno Kristiaan Bernard De Man , Peter Michael Edic , Jiang Hsieh
Abstract: The present approach provides a non-invasive methodology for estimation of coronary flow and/or fractional flow reserve. In certain implementations, various approaches for personalizing blood flow models of the coronary vasculature are described. The described personalization approaches involve patient-specific measurements and do not assume or rely on the resting coronary flow being proportional to myocardial mass. Consequently, there are fewer limitations in using these approaches to obtain coronary flow and/or fractional flow reserve estimates non-invasively.
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公开(公告)号：US20170218769A1
公开(公告)日：2017-08-03
申请号：US15010145
申请日：2016-01-29
Applicant: General Electric Company
Inventor： Prem Venugopal , Alexander Stein , Shourya Prakash Otta , Ambady Suresh
CPC classification number: F01D5/145 , F01D5/143 , F05D2220/32 , F05D2240/24 , F05D2240/81 , F05D2250/711 , F05D2250/712 , Y02T50/673
Abstract: A turbine stage includes a row of airfoils joined to corresponding platforms to define flow passages therebetween. Each airfoil includes opposite pressure and suction sides and extends in chord between opposite leading and trailing edges. Each platform has a contoured flow surface including a purge valley, an elevated bulge and a bowl. The purge valley has a maximum depth at an elevation equal to or greater than a nominal axisymmetric platform surface of the corresponding platform. The purge valley extending tangentially against a purge cavity wall and into the blend area and extending axially from proximate the leading edge of a first airfoil toward the suction side of the first airfoil, and toward the leading edge of a second adjacent airfoil to channel a purge flow. The elevated bulge adjoins the pressure side aft of the leading edge and the bowl adjoins the suction side aft of the leading edge.
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