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公开(公告)号:US10570192B2
公开(公告)日:2020-02-25
申请号:US15718876
申请日:2017-09-28
Applicant: Genentech, Inc.
Inventor: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: C07K16/12 , A61K39/40 , A61K31/5386 , A61K45/06 , A61K31/4025 , A61K47/68
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US20190233491A1
公开(公告)日:2019-08-01
申请号:US16128008
申请日:2018-09-11
Applicant: Genentech, Inc.
Inventor: Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Ganesh A. Kolumam , Xiaoting Wang , Jed Ross , Nicholas Van Bruggen , Wyne P. Lee
CPC classification number: C07K14/54 , A61K38/00 , A61K38/20 , A61K47/38 , C07K16/2866 , C07K2319/30
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号:US20150366985A1
公开(公告)日:2015-12-24
申请号:US14284619
申请日:2014-05-22
Applicant: GENENTECH, INC.
Inventor: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: A61K47/48 , A61K31/395
CPC classification number: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
Abstract translation: 本发明提供了抗壁磷壁酸抗体及其抗生素缀合物及其使用方法。
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公开(公告)号:US20140356375A1
公开(公告)日:2014-12-04
申请号:US14284609
申请日:2014-05-22
Applicant: GENENTECH, INC.
Inventor: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: C07K16/12 , A61K39/40 , A61K31/5383 , A61K47/48
CPC classification number: C07K16/1271 , A61K31/5383 , A61K47/6809 , A61K47/6835 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
Abstract translation: 本发明提供了抗壁磷壁酸抗体及其抗生素缀合物及其使用方法。
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公开(公告)号:US11130791B2
公开(公告)日:2021-09-28
申请号:US16196936
申请日:2018-11-20
Applicant: Genentech, Inc.
Inventor: Justin Scheer , Wenjun Ouyang , Eric Gary Stefanich , Richard Vandlen , Philip E. Hass , Xiaoting Wang
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号:US20190177390A1
公开(公告)日:2019-06-13
申请号:US16196936
申请日:2018-11-20
Applicant: Genentech, Inc.
Inventor: Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Ganesh A. Kolumam , Xiaoting Wang , Jed Ross , Nicholas Van Bruggen , Wyne P. Lee
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号:US20180085470A1
公开(公告)日:2018-03-29
申请号:US15834740
申请日:2017-12-07
Applicant: Genentech, Inc.
Inventor: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: A61K31/7056 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , C07K16/12 , A61K38/12 , A61K31/7048 , A61K31/4709
CPC classification number: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies, antibiotic-linker intermediates, and antibody-antibiotic conjugate compound, and methods of making and using the same.
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公开(公告)号:US09895450B2
公开(公告)日:2018-02-20
申请号:US14945716
申请日:2015-11-19
Applicant: Genentech, Inc.
Inventor: Eric J. Brown , John Flygare , Wouter Hazenbos , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: A61K39/395 , A61K47/48 , C07K16/12 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12
CPC classification number: A61K47/6849 , A61K31/395 , A61K31/4375 , A61K31/439 , A61K31/4436 , A61K31/4709 , A61K31/7048 , A61K31/7056 , A61K38/12 , A61K47/6801 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K47/6851 , C07K16/1271 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US09803002B2
公开(公告)日:2017-10-31
申请号:US14292289
申请日:2014-05-30
Applicant: Genentech, Inc.
Inventor: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: A61K39/40 , C07K16/12 , A61K31/5386 , A61K45/06 , A61K31/4025 , A61K47/68
CPC classification number: C07K16/1271 , A61K31/4025 , A61K31/5386 , A61K39/40 , A61K45/06 , A61K47/6809 , A61K47/6835 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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公开(公告)号:US20140356376A1
公开(公告)日:2014-12-04
申请号:US14292289
申请日:2014-05-30
Applicant: Genentech, Inc.
Inventor: Eric J. Brown , Martine Darwish , John Flygare , Wouter Hazenbos , Byoung Chul Lee , Sophie M. Lehar , Sanjeev Mariathasan , John Hiroshi Morisaki , Thomas H. Pillow , Leanna Staben , Richard Vandlen , Klaus Koefoed , Magnus Strandh , Peter S. Andersen
IPC: C07K16/12 , A61K31/4025 , A61K47/48 , A61K45/06 , A61K39/40 , A61K31/5386
CPC classification number: C07K16/1271 , A61K31/4025 , A61K31/5386 , A61K39/40 , A61K45/06 , A61K47/6809 , A61K47/6835 , C07K2317/21 , C07K2317/522 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/624 , C07K2317/92
Abstract: The invention provides anti-wall teichoic acid antibodies and antibiotic conjugates thereof, and methods of using the same.
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