公开(公告)号：US11344849B2

公开(公告)日：2022-05-31

申请号：US15565307

申请日：2016-06-07

Applicant: Becton, Dickinson and Company

Inventor： Qihua Xu ,  Alexander G. Lastovich

IPC: B01D61/18 ,  B01D63/08 ,  B01D71/50 ,  B01D61/14 ,  A61M1/34 ,  B01D67/00 ,  A61M1/36 ,  A61M1/16

Abstract: A filtration cell (10) for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane (14) positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed.

公开(公告)号：US20140018734A1

公开(公告)日：2014-01-16

申请号：US13780993

申请日：2013-02-28

Applicant: Becton, Dickinson and Company

Inventor： Paul G. Alchas ,  M. Ishaq Haider ,  Alexander G. Lastovich ,  Frank E. Martin

IPC: A61M5/42

CPC classification number: A61M5/425 ,  A61M5/14244 ,  A61M5/3007 ,  A61M5/46 ,  A61M37/0015

Abstract: An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. The device may include a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid.

Abstract translation: 提供了一种用于通过至少一层皮肤递送或取出流体的装置。 该装置可以包括具有顶面，底面，侧边缘和至少一个通道的主体。 底面包括与第一表面区域相邻并且与第一表面区域第一距离凹陷的第一表面区域和第二表面区域。 底面还包括设置在第二表面区域上的至少一个凸起突起。 突起具有从第一表面的高度大于第一距离。 在突起中提供至少一个真皮进入构件，并且与通道流体连通以输送或抽出流体。