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24 条记录 (耗时 0.017 秒)

    Screen-based interactive image-plane prescription for MRI
    11.
    发明授权
    Screen-based interactive image-plane prescription for MRI 失效
    用于MRI的基于屏幕的交互式图像平面处方

    公开(公告)号：US5512826A

    公开(公告)日：1996-04-30

    申请号：US458601

    申请日：1995-06-02

    申请人： Christopher J. Hardy ,  Robert D. Darrow

    发明人： Christopher J. Hardy ,  Robert D. Darrow

    IPC分类号： G01R33/54 ,  G01R33/48

    CPC分类号： G01R33/54 ,  G01R33/543 ,  G01R33/546

    摘要： An MR image of a subject is displayed on a display device. Scan-control icons are displayed over this image. An operator interacts with an interface device to select imaging plane parameters during imaging. This is performed by selecting one of the icons with a pointing device, and dragging. Interface device then provides a display which indicates the motion of the imaging plane as well as the extent of the motion. Once selected, the location and orientation information transformed to global coordinates and is provided to a pulse sequencer of a magnetic resonance (MR) imaging system. The pulse sequencer controls an RF transmitter and gradient amplifiers to cause an MR image of the subject at an imaging plane to be acquired. This allows fast, accurate imaging plane selection, which may be selected by an operator who is searching for structures within the subject, or who is simultaneously performing a medical procedure on the subject.

    摘要翻译： 主体的MR图像显示在显示装置上。 扫描控制图标显示在此图像上。 操作者与接口设备进行交互以在成像期间选择成像平面参数。 这是通过使用指点设备选择一个图标并拖动来执行的。 然后，接口装置提供指示成像平面的运动以及运动程度的显示器。 一旦被选择，将位置和方位信息变换为全局坐标并提供给磁共振（MR）成像系统的脉冲序列器。 脉冲序列发生器控制RF发射器和梯度放大器，以获得成像平面上的对象的MR图像。 这允许快速，精确的成像平面选择，其可以由正在搜索对象内的结构的操作者选择，或者同时对该对象执行医疗程序。

    Heat surgery system monitored by real-time magnetic resonance temperature profiling
    13.
    发明授权
    Heat surgery system monitored by real-time magnetic resonance temperature profiling 失效
    热手术系统通过实时磁共振温度分析进行监测

    公开(公告)号：US5323779A

    公开(公告)日：1994-06-28

    申请号：US162987

    申请日：1993-12-08

    申请人： Christopher J. Hardy ,  Harvey E. Cline

    发明人： Christopher J. Hardy ,  Harvey E. Cline

    IPC分类号： G01R33/20 ,  A61B5/055 ,  A61B18/00 ,  A61B18/20 ,  A61B18/24 ,  A61B19/00 ,  A61N7/00 ,  A61N7/02 ,  G01R33/48 ,  G01R33/561

    CPC分类号： A61N7/02 ,  A61B18/24 ,  G01R33/4804 ,  G01R33/561 ,  A61B2090/374 ,  G01R33/56308

    摘要： Surgery is performed with a pulsed heat-producing device that selectively heats a region in a specific tissue within a patient destroying the tissue. The pulsed heat-producing device may be a coherent optical source that is guided by laser fiber to the tissue to be destroyed. In another embodiment, the pulsed heat-producing device is a focussed ultrasound transducer which concentrates ultrasonic energy at a focal point within the specific tissue. A magnetic resonance imaging system employing a real-time temperature-sensitive pulse sequence monitors the heated region of the tissue to provide temperature profiles allowing an operator to alter the position and size of the heated region.

    摘要翻译： 使用脉冲发热装置进行手术，该装置选择性地加热破坏组织的患者内的特定组织中的区域。 脉冲发热装置可以是由激光纤维引导到要破坏的组织的相干光源。 在另一个实施例中，脉冲发热装置是聚焦的超声换能器，其将超声能量集中在特定组织内的焦点处。 使用实时温度敏感脉冲序列的磁共振成像系统监测组织的加热区域以提供温度分布，允许操作者改变加热区域的位置和尺寸。

    Polarization transfer by selective homonuclear technique for suppression of uncoupled spins in NMR spectroscopy
    15.
    发明授权
    Polarization transfer by selective homonuclear technique for suppression of uncoupled spins in NMR spectroscopy 失效
    通过选择性同核技术在NMR光谱学中抑制非偶联自旋的极化转移

    公开(公告)号：US4701708A

    公开(公告)日：1987-10-20

    申请号：US891823

    申请日：1986-08-01

    申请人： Christopher J. Hardy ,  Charles L. Dumoulin

    发明人： Christopher J. Hardy ,  Charles L. Dumoulin

    IPC分类号： A61B5/055 ,  G01R33/20 ,  G01R33/32 ,  G01R33/46

    CPC分类号： G01R33/4608

    摘要： A method of suppressing at least one undesired resonance response signal while facilitating reception of at least one other desired NMR response signal from a coupled spin resonance in NMR spectroscopy, utilizes a pair of alternating sequences of RF signal pulses, with each sequence having an initial .pi./2 RF pulse, followed by a .pi. RF signal pulse having a temporal midpoint at a time interval T after the temporal midpoint of the initial pulse (where T=n/4J, with n being an odd integer and J being the spin coupling constant of the hydrogen nuclei) and a final .pi. RF signal pulse with a temporal midpoint at twice the time interval T after the temporal midpoint of the first .pi. RF signal pulse in that sequence. Only one of the pair of sequences is provided with a polarization transfer narrowband .pi. RF signal pulse symmetrically disposed about a temporal midpoint located at substantially a time interval T after the first .pi. RF signal pulse of that sequence and substantially at a frequency removed from the resonance frequency of at least one undesired uncoupled spin resonance. Response signals are acquired within a gating period including a temporal point thereof occurring at a time interval T after the temporal midpoint of the final .pi. RF signal pulse. The pair of recovered sets of data are substracted from one another to obtain a final data set in which noncoupled spin resonance data is substantially cancelled but desired coupled spin resonance data is preserved.

    摘要翻译： 抑制至少一种不期望的共振响应信号的方法同时有利于从NMR光谱中从耦合的自旋共振接收至少一种其它期望的NMR响应信号，利用一对RF信号脉冲的交替序列，其中每个序列具有初始pI / 2 RF脉冲，其后是在初始脉冲的时间中点（其中T = n / 4J，其中n为奇整数，J为自旋耦合常数）的时间间隔T之后具有时间中点的pi RF信号脉冲 的氢核）和最终的pi RF信号脉冲，其具有在该序列中的第一pi RF信号脉冲的时间中点之后的时间间隔T的两倍的时间中点。 该对序列中只有一个被提供有偏振转移窄带pi RF信号脉冲，该偏振转移窄带pi RF信号脉冲对称地设置在该序列的第一pi RF信号脉冲之后的基本上位于时间间隔T的时间中点处，并且基本上以从谐振 至少一个不期望的非偶联自旋共振的频率。 响应信号在门控周期内获取，包括在最终的pi RF信号脉冲的时间中点之后的时间间隔T出现的时间点。 一对恢复的数据集彼此相减，以获得最终数据集，其中非耦合自旋共振数据被基本上取消，但保留了所需的耦合自旋谐振数据。

    Spectroscopic localization using pinwheel NMR excitation pulses
    16.
    发明授权
    Spectroscopic localization using pinwheel NMR excitation pulses 失效
    使用PINHEEL NMR激发脉冲进行光谱定位

    公开(公告)号：US5192909A

    公开(公告)日：1993-03-09

    申请号：US637910

    申请日：1991-01-07

    申请人： Christopher J. Hardy ,  Paul A. Bottomley ,  Harvey E. Cline

    发明人： Christopher J. Hardy ,  Paul A. Bottomley ,  Harvey E. Cline

    IPC分类号： A61B5/055 ,  G01R33/48

    CPC分类号： G01R33/446

    摘要： An NMR system performs in vivo localized NMR spectroscopy. A two-dimensional selective RF excitation pulse is used to localize to a cylindrical region of interest, and either phase encoding or slice selective inversion is used to localize to a disk in the cylindrical region of interest. The two-dimensional selective RF excitation is performed in a series of pulse sequences rather than a single pulse sequence, and the resulting series of acquired NMR signals are summed together to substantially cancel signal conributions from outside the cylindrical region of interest.

    摘要翻译： NMR体系进行体内局部NMR光谱。 使用二维选择性RF激励脉冲来定位到感兴趣的圆柱形区域，并且使用相位编码或切片选择性反转来定位到感兴趣的圆柱形区域中的盘。 二维选择性RF激励以一系列脉冲序列而不是单个脉冲序列执行，并且所得到的一系列获取的NMR信号被相加在一起以基本上消除来自感兴趣的圆柱体区域的信号。

    NMR probe with multiple isolated coplanar surface coils
    17.
    发明授权
    NMR probe with multiple isolated coplanar surface coils 失效
    具有多个隔离的共面表面线圈的NMR探针

    公开(公告)号：US4973908A

    公开(公告)日：1990-11-27

    申请号：US370518

    申请日：1989-06-23

    申请人： Paul A. Bottomley ,  Christopher J. Hardy

    发明人： Paul A. Bottomley ,  Christopher J. Hardy

    IPC分类号： G01R33/36 ,  A61B5/055 ,  G01R33/32 ,  G01R33/34 ,  G01R33/341

    CPC分类号： G01R33/341

    摘要： An NMR antenna probe has at least one substantially circular surface coil arranged in a plane and a surface coil having substantially a Figure-8 shape, substantially coplanar with the at least one circular surface coil. The Figure-8 coil has a cross-over portion which is located substantially coaxial with the axis of the at least one circular surface coil. The coil corresponding to the least-NMR-sensitive nucleus is circular, while the non-circular coil corresponds to the most-NMR-sensitive nucleus. The circular coil is positioned on the side of the NMR probe closest to the subject to be studied.

    NMR magnetization inversion by non-linear adiabatic fast passage
    18.
    发明授权
    NMR magnetization inversion by non-linear adiabatic fast passage 失效
    通过非线性绝热快速通过NMR磁化反演

    公开(公告)号：US4695799A

    公开(公告)日：1987-09-22

    申请号：US746146

    申请日：1985-06-18

    申请人： Christopher J. Hardy ,  William A. Edelstein

    发明人： Christopher J. Hardy ,  William A. Edelstein

    IPC分类号： A61B5/055 ,  A61B10/00 ,  G01R33/36 ,  G01R33/46 ,  G01R33/48 ,  G01R33/20

    CPC分类号： G01R33/446 ,  G01R33/3607

    摘要： A method for the complete inversion of magnetization by adiabatic fast passage during an NMR experiment on a sample having a selected nuclear specie with a Larmor frequency .omega..sub.0. A radio-frequency magnetic field is generated with an amplitude B.sub.1 and an instantaneous frequency .omega.(t) which is non-linearly swept, as a function of time, from a minimum frequency .omega..sub.1 substantially at a maximum offset frequency .DELTA..omega. below the Larmor frequency .omega..sub.0, through the Larmor frequency, to a maximum frequency .omega..sub.h substantially at the maximum offset frequency .DELTA..sub..omega. above the Larmor frequency. The non-linearly swept, monotonic RF signal is applied to the sample-being-investigated for a sweep time interval sufficient to invert the magnetization of the selected nuclear specie. The preferred sweep is a tangential function:.omega.(t)=.omega..sub.0 .+-..gamma.B.sub.1 tan (arcsin (.omega..sub.s t)), (A)or.omega.(t)=.omega..sub.0 .+-..gamma.B.sub.1 tan (.omega..sub.s t)where .omega..sub.s =.alpha..gamma.B.sub.1, .gamma. is the gyromagnetic ratio of the selected nuclear specie and 0

    摘要翻译： 在具有Larmor频率ω0的选定核子样品的NMR实验中通过绝热快速通过完全反转磁化的方法。产生具有振幅B1和瞬时频率ω（t）的射频磁场 ），其通过拉莫尔频率从基本上在低于拉莫尔频率ω0的最大偏移频率DELTAω的基本上最大频率ω1的最小频率ω1作为时间的非线性扫描到最大频率ωh 偏移频率DELTA omega高于拉莫尔频率。 将非线性扫描的单调RF信号施加到被研究的样品的扫描时间间隔，以足以反转所选择的核物种的磁化。 优选的扫描是切向函数：ω（t）=ω0 +/-γB1 tan（arcsin（ω）），（A）或ω（t）=ω0 +/-γB1 tan（ω） 其中ω=α伽马B1，γ是所选核物种的回磁比，0≤α= 1。

    Time-line imaging-plane prescription for MRI
    19.
    发明授权
    Time-line imaging-plane prescription for MRI 失效
    MRI的时间线成像平面处方

    公开(公告)号：US5584293A

    公开(公告)日：1996-12-17

    申请号：US515786

    申请日：1995-08-16

    申请人： Robert D. Darrow ,  Christopher J. Hardy

    发明人： Robert D. Darrow ,  Christopher J. Hardy

    IPC分类号： G01R33/28 ,  A61B5/055 ,  G01R33/54 ,  G06T1/00 ,  A61B5/05

    CPC分类号： G01R33/54

    摘要： Imaging parameters, such as the location, orientation and field of view of an imaging plane are selected. These parameters are provided to a pulse sequencer of a magnetic resonance (MR) scanner which modifies an MR pulse sequence to acquire an image at the selected imaging plane. The pulse sequencer controls an RF transmitter and gradient amplifiers to cause an MR image of the subject at an imaging plane to be acquired. The MR image is displayed on a display device. An interface device receives and reduces the MR image to an image icon and saves the image icon along with the corresponding imaging parameters. The image icons are displayed on the periphery of the screen around an MR image. An operator may then view and select one of the image icons, employing the pointing device. This causes the imaging parameters corresponding to the selected image icon to be sent to the pulse sequencer thereby causing an MR image to be acquired with these imaging parameters.

    摘要翻译： 选择成像参数，例如成像平面的位置，方位和视场。 这些参数被提供给磁共振（MR）扫描器的脉冲序列器，其修改MR脉冲序列以获取所选成像平面上的图像。 脉冲序列发生器控制RF发射器和梯度放大器，以获得成像平面上的对象的MR图像。 MR图像显示在显示设备上。 接口装置将MR图像接收并减少到图像图标，并将图像图标与相应的成像参数一起保存。 图像图标显示在MR图像周围的屏幕周围。 然后，操作者可以使用指示设备来查看和选择一个图像图标。 这使得与所选择的图像图标相对应的成像参数被发送到脉冲序列器，从而使得利用这些成像参数获取MR图像。