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公开(公告)号:US10080484B2
公开(公告)日:2018-09-25
申请号:US14611015
申请日:2015-01-30
Applicant: University of Washington
Inventor: Chenying Yang , Eric J. Seibel , Leonard Y. Nelson , Timothy D. Soper
IPC: A61B6/00 , A61B1/04 , G02B23/26 , G01N21/64 , A61B1/00 , G01J3/06 , G01J3/10 , G01J3/28 , G01J3/36 , G01J3/44 , G01N21/27 , G01N21/47 , G01J3/02
CPC classification number: A61B1/043 , A61B1/00009 , A61B1/00165 , A61B1/00172 , G01J3/0208 , G01J3/0218 , G01J3/0278 , G01J3/06 , G01J3/10 , G01J3/28 , G01J3/36 , G01J3/4406 , G01J2003/065 , G01N21/278 , G01N21/474 , G01N21/6456 , G01N21/6486 , G01N2021/4742 , G01N2021/6417 , G01N2021/6419 , G01N2021/6484 , G02B23/26 , G02B26/103
Abstract: Improved methods, systems and apparatus relating to wide field fluorescence and reflectance imaging are provided, including improved methods, systems and apparatus relating to removal of background signals such as autofluorescence and/or fluorophore emission cross-talk; distance compensation of fluorescent signals; and co-registration of multiple signals emitted from three dimensional tissues.
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公开(公告)号:US09554729B2
公开(公告)日:2017-01-31
申请号:US14951279
申请日:2015-11-24
Applicant: University of Washington
Inventor: Timothy D. Soper , Robb W. Glenny , Eric J. Seibel
IPC: A61B1/04 , A61B1/00 , A61B5/06 , A61B1/267 , A61B1/005 , A61B1/07 , A61B5/08 , A61B5/00 , A61B6/00 , A61B19/00
CPC classification number: A61B5/066 , A61B1/00009 , A61B1/00016 , A61B1/00045 , A61B1/0008 , A61B1/00172 , A61B1/005 , A61B1/04 , A61B1/07 , A61B1/2676 , A61B5/06 , A61B5/062 , A61B5/065 , A61B5/08 , A61B5/0816 , A61B5/7285 , A61B6/541 , A61B34/20 , A61B2034/2051 , A61B2090/3762
Abstract: Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.
Abstract translation: 在支气管镜检查过程期间,将超薄柔性内窥镜视觉辅助引导到肺内的预定感兴趣区域。 该区域可以是通过非侵入性成像方法识别的不透明度,例如高分辨率计算机断层摄影(HRCT)或作为在以前检查中诊断的恶性肺肿块。 柔性内窥镜上的嵌入式位置传感器在手术过程中指示探针的远端在笛卡尔坐标系中的位置。 视觉显示不断更新,显示了从图像重建产生的3-D图形气道模型中的标记的当前位置和方向。 视觉显示还包括描绘虚拟透视透视图和在内窥镜头部处获取的实时视频图像的窗口,其可以作为数据存储,具有音频或文本帐户。
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3.
公开(公告)号:US20160073928A1
公开(公告)日:2016-03-17
申请号:US14951279
申请日:2015-11-24
Applicant: University of Washington
Inventor: Timothy D. Soper , Robb W. Glenny , Eric J. Seibel
CPC classification number: A61B5/066 , A61B1/00009 , A61B1/00016 , A61B1/00045 , A61B1/0008 , A61B1/00172 , A61B1/005 , A61B1/04 , A61B1/07 , A61B1/2676 , A61B5/06 , A61B5/062 , A61B5/065 , A61B5/08 , A61B5/0816 , A61B5/7285 , A61B6/541 , A61B34/20 , A61B2034/2051 , A61B2090/3762
Abstract: Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.
Abstract translation: 在支气管镜检查过程期间,将超薄柔性内窥镜视觉辅助引导到肺内的预定感兴趣区域。 该区域可以是通过非侵入性成像方法识别的不透明度,例如高分辨率计算机断层摄影(HRCT)或作为在以前检查中诊断的恶性肺肿块。 柔性内窥镜上的嵌入式位置传感器在手术过程中指示探针的远端在笛卡尔坐标系中的位置。 视觉显示不断更新,显示了从图像重建产生的3-D图形气道模型中的标记的当前位置和方向。 视觉显示还包括描绘虚拟透视透视图和在内窥镜头部获取的实时视频图像的窗口,其可以作为数据存储,具有音频或文本帐户。
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4.
公开(公告)号:US20150216398A1
公开(公告)日:2015-08-06
申请号:US14611015
申请日:2015-01-30
Applicant: University of Washington
Inventor: Chenying Yang , Eric J. Seibel , Leonard Y. Nelson , Timothy D. Soper
CPC classification number: A61B1/043 , A61B1/00009 , A61B1/00165 , A61B1/00172 , G01J3/0208 , G01J3/0218 , G01J3/0278 , G01J3/06 , G01J3/10 , G01J3/28 , G01J3/36 , G01J3/4406 , G01J2003/065 , G01N21/278 , G01N21/474 , G01N21/6456 , G01N21/6486 , G01N2021/4742 , G01N2021/6417 , G01N2021/6419 , G01N2021/6484 , G02B23/26 , G02B26/103
Abstract: Improved methods, systems and apparatus relating to wide field fluorescence and reflectance imaging are provided, including improved methods, systems and apparatus relating to removal of background signals such as autofluorescence and/or fluorophore emission cross-talk; distance compensation of fluorescent signals; and co-registration of multiple signals emitted from three dimensional tissues.
Abstract translation: 提供了与宽场荧光和反射成像相关的改进的方法,系统和装置,包括与去除背景信号(例如自发荧光和/或荧光团发射串扰)有关的改进方法,系统和装置; 荧光信号距离补偿; 以及从三维组织发射的多个信号的共同配准。
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公开(公告)号:US09226687B2
公开(公告)日:2016-01-05
申请号:US13742889
申请日:2013-01-16
Applicant: University of Washington
Inventor: Timothy D. Soper , Robb W. Glenny , Eric J. Seibel
IPC: A61B1/04 , A61B1/00 , A61B5/06 , A61B1/267 , A61B19/00 , A61B1/005 , A61B5/08 , A61B5/00 , A61B6/00
CPC classification number: A61B5/066 , A61B1/00009 , A61B1/00016 , A61B1/00045 , A61B1/0008 , A61B1/00172 , A61B1/005 , A61B1/04 , A61B1/07 , A61B1/2676 , A61B5/06 , A61B5/062 , A61B5/065 , A61B5/08 , A61B5/0816 , A61B5/7285 , A61B6/541 , A61B34/20 , A61B2034/2051 , A61B2090/3762
Abstract: Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.
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