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公开(公告)号:US20170232026A1
公开(公告)日:2017-08-17
申请号:US15503033
申请日:2015-08-12
Applicant: UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO
Inventor: David QUINTANAR GUERRERO , Juan Pablo MARTINEZ LABAT , Susana Elisa MENDOZA ELVIRA , Gustavo VIDAL ROMERO , Victor Andres TRENADO HERNANDEZ
CPC classification number: A61K31/7048 , A61K9/0017 , A61K9/06 , A61K47/10 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/44
Abstract: The invention relates to a pharmaceutical composition comprising: at least one antiparasitic active ingredient for providing the pharmacological therapeutic effect; an agent having bio-adhesive properties that helps to reduce the motility and reproduction of the parasites, increasing the period of time for which the product remains on the skin of the animals; an agent having permeation- or absorption-promoting properties that contributes to increasing the cutaneous permeability of the active ingredient; a surfactant agent that is absorbed in an oil-water interface, and as a result, the molecules of said surfactant agent form a kind of bridge between the polar phase (water) and the non-polar phase (oil), thereby making the transition between both phases less abrupt; an oil which will form the oily phase of the emulsion, and which will incorporate the active ingredient; and a neutralizing agent.