公开(公告)号：US11382574B2

公开(公告)日：2022-07-12

申请号：US16761543

申请日：2018-11-06

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Wenxiang Cong ,  Qingsong Yang ,  Guang Li

IPC: A61B6/03 ,  A61B6/00 ,  G01N23/041

Abstract: A stationary in-vivo grating-enabled micro-CT (computed tomography) architecture (SIGMA) system includes CT scanner control circuitry and a number of imaging chains. Each imaging chain includes an x-ray source array, a phase grating, an analyzer grating and a detector array. Each imaging chain is stationary and each x-ray source array includes a plurality of x-ray source elements. Each imaging chain has a centerline, the centerlines of the number of imaging chains intersect at a center point and a first angle between the centerlines of a first adjacent pair of imaging chains equals a second angle between the centerlines of a second adjacent pair of imaging chains. A plurality of selected x-ray source elements of a first x-ray source array is configured to emit a plurality of x-ray beams in a multiplexing fashion.

公开(公告)号：US20210080409A1

公开(公告)日：2021-03-18

申请号：US16955939

申请日：2018-12-20

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Guang Li ,  Wenxiang Cong

IPC: G01N23/20008 ,  G01N23/201

Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementarity second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.

公开(公告)号：US11232541B2

公开(公告)日：2022-01-25

申请号：US16594567

申请日：2019-10-07

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Chenyu You ,  Wenxiang Cong ,  Hongming Shan ,  Guang Li

IPC: G06T3/40 ,  G06N3/04

Abstract: A system for generating a high resolution (HR) computed tomography (CT) image from a low resolution (LR) CT image is described. The system includes a first generative adversarial network (GAN) and a second GAN. The first GAN includes a first generative neural network (G) configured to receive a training LR image dataset and to generate a corresponding estimated HR image dataset, and a first discriminative neural network (DY) configured to compare a training HR image dataset and the estimated HR image dataset. The second GAN includes a second generative neural network (F) configured to receive the training HR image dataset and to generate a corresponding estimated LR image dataset, and a second discriminative neural network (DX) configured to compare the training LR image dataset and the estimated LR image dataset. The system further includes an optimization module configured to determine an optimization function based, at least in part, on at least one of the estimated HR image dataset and/or the estimated LR image dataset. The optimization function contains at least one loss function. The optimization module is further configured to adjust a plurality of neural network parameters associated with at least one of the first GAN and/or the second GAN, to optimize the optimization function.

公开(公告)号：US11313814B2

公开(公告)日：2022-04-26

申请号：US16955939

申请日：2018-12-20

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Guang Li ,  Wenxiang Cong

IPC: G01N23/20008 ,  G01N23/201 ,  G01N23/046 ,  G21K1/02 ,  A61B6/03

Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementary second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the grating are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.

公开(公告)号：US20200261030A1

公开(公告)日：2020-08-20

申请号：US16761543

申请日：2018-11-06

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Wenxiang Cong ,  Qingsong Yang ,  Guang Li

IPC: A61B6/03 ,  A61B6/00

Abstract: A stationary in-vivo grating-enabled micro-CT (computed tomography) architecture (SIGMA) system includes CT scanner control circuitry and a number of imaging chains. Each imaging chain includes an x-ray source array, a phase grating, an analyzer grating and a detector array. Each imaging chain is stationary and each x-ray source array includes a plurality of x-ray source elements. Each imaging chain has a centerline, the centerlines of the number of imaging chains intersect at a center point and a first angle between the centerlines of a first adjacent pair of imaging chains equals a second angle between the centerlines of a second adjacent pair of imaging chains. A plurality of selected x-ray source elements of a first x-ray source array is configured to emit a plurality of x-ray beams in a multiplexing fashion.

公开(公告)号：US11592406B2

公开(公告)日：2023-02-28

申请号：US17711171

申请日：2022-04-01

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Guang Li ,  Wenxiang Cong

IPC: G01N23/201 ,  G01N23/20008 ,  A61B6/00

Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementary second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.

公开(公告)号：US20220221413A1

公开(公告)日：2022-07-14

申请号：US17711171

申请日：2022-04-01

Applicant: RENSSELAER POLYTECHNIC INSTITUTE

Inventor： Ge Wang ,  Guang Li ,  Wenxiang Cong

IPC: G01N23/20008 ,  G01N23/201 ,  G21K1/02 ,  A61B6/03 ,  G01N23/046

Abstract: A detection scheme for x-ray small angle scattering is described. An x-ray small angle scattering apparatus may include a first grating and a complementary second grating. The first grating includes a plurality of first grating cells. The complementary second grating includes a plurality of second grating cells. The second grating is positioned relative to the first grating. A configuration of the first grating, a configuration of the second grating and the relative positioning of the gratings are configured to pass one or more small angle scattered photons and to block one or more Compton scattered photons and one or more main x-ray photons.