公开(公告)号：US20140072987A1

公开(公告)日：2014-03-13

申请号：US14025623

申请日：2013-09-12

Applicant: RANDOX LABORATORIES LTD.

Inventor： Mark W. Ruddock ,  Cherith N. Reid ,  Kathleen Williamson ,  John V. Lamont ,  Stephen P. Fitzgerald

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N33/57407 ,  G01N2800/52 ,  G01N2800/60

Abstract: The disclosure relates to methods of detecting bladder cancer including assaying a patient sample for the levels of certain combinations of biomarkers. The disclosure also relates to methods for determining the efficacy of a drug for the treatment of bladder cancer.

Abstract translation: 本公开涉及检测膀胱癌的方法，包括测定患者样品中生物标志物的某些组合的水平。 本公开还涉及用于确定药物治疗膀胱癌的功效的方法。

公开(公告)号：US20180011115A1

公开(公告)日：2018-01-11

申请号：US15547608

申请日：2016-01-29

Applicant: Randox Laboratories Ltd.

Inventor： Mark W. Ruddock ,  Cherith N. Reid ,  Kate E. Williamson ,  John Lamont ,  Peter Fitzgerald

IPC: G01N33/86

CPC classification number: G01N33/86 ,  G01N33/57407 ,  G01N33/6893 ,  G01N2800/50 ,  G01N2800/709

Abstract: The present invention related to a method for detecting a history of exposure to a chemical(s) comprising measuring the concentration of thrombomodulin in a sample isolated from a subject, and determining whether the concentration of thrombomodulin is altered compared to control reference levels.