公开(公告)号：US20230142476A1

公开(公告)日：2023-05-11

申请号：US17980820

申请日：2022-11-04

Applicant: POSTECH Research and Business Development Foundation ,  UNIST(ULSAN National Institute of Science and Technology)

Inventor： Dong Sung Kim ,  Tae Eun Park ,  Hyeon Ji Lim ,  Do Hui Kim

IPC: C12N5/071

CPC classification number: C12N5/0697 ,  C12N2506/45 ,  C12N2501/16 ,  C12N2501/119 ,  C12N2500/02 ,  C12N2513/00

Abstract: Disclosed is a method for producing kidney organoids including steps of: (1) differentiating stem cells into metanephric mesenchyme cells; (2) forming metanephric mesenchyme cell aggregates by culturing the metanephric mesenchyme cells; and (3) differentiating the metanephric mesenchyme cell aggregates into kidney organoids.

公开(公告)号：US20220315678A1

公开(公告)日：2022-10-06

申请号：US17700686

申请日：2022-03-22

Applicant: POSTECH Research and Business Development Foundation

Inventor： Dong Sung Kim ,  Hyeon Seok Han ,  Andrew Choi

IPC: C08F120/56 ,  C08F2/50 ,  F03G7/06

Abstract: The invention relates to a water responsive soft actuator using water responsive hydrogel whose volume hardly changes, and a method for driving the soft actuator. The water responsive soft actuator according to the invention includes polyisopropylacrylamide, and the polyisopropylacrylamide has an N-isopropylacrylamide monomer and water in a weight ratio of 87:13 to 95:5, wherein the water responsive soft actuator is driven by water absorption of the polyisopropylacrylamide.