公开(公告)号：US20180312484A1

公开(公告)日：2018-11-01

申请号：US15772833

申请日：2016-11-03

申请人： Mylan Laboratories Limited

发明人： Sureshbabu Jayachandra ,  Vipin Kumar Kaushik ,  Vijaya Krishna RAVI ,  Vikas Chandra Dev ,  Saiprasad Kottolla ,  Potla Venkata Srinivasa Rao ,  Srinivas Vakiti ,  Chaitanya Muggu ,  Subramanyam Dandala

IPC分类号： C07D307/33 ,  C07D319/12

CPC分类号： C07D307/33 ,  C07D307/20 ,  C07D319/12

摘要： A process for the preparation of intermediates 9, useful in the synthesis of sofosbuvir, as well as intermediates of formula [12] are disclosed herein.

公开(公告)号：US11466031B2

公开(公告)日：2022-10-11

申请号：US17050531

申请日：2019-04-25

申请人： Mylan Laboratories Limited

发明人： Ramakoteswara Rao Jetti ,  Daveedu Bhatraju ,  Subramanyam Dandala ,  Aggi Ramireddy Bommareddy ,  Rajendar Reddy Mulamalla ,  Sridhar Tailor ,  Sureshbabu Jayachandra

IPC分类号： C07D498/22

摘要： The present disclosure provides crystalline forms of bictegravir, amorphous bictegravir sodium, amorphous solid dispersion of bictegravir sodium with pharmaceutically acceptable carrier and processes for the preparation thereof.

公开(公告)号：US10344009B2

公开(公告)日：2019-07-09

申请号：US15772833

申请日：2016-11-03

申请人： Mylan Laboratories Limited

发明人： Sureshbabu Jayachandra ,  Vipin Kumar Kaushik ,  Vijaya Krishna Ravi ,  Vikas Chandra Dev ,  Saiprasad Kottolla ,  Potla Venkata Srinivasa Rao ,  Srinivas Vakiti ,  Chaitanya Muggu ,  Subramanyam Dandala

IPC分类号： C07D307/33 ,  C07D319/12 ,  C07D307/20

摘要： A process for the preparation of intermediates 9, useful in the synthesis of sofosbuvir, as well as intermediates of formula [12] are disclosed herein.