公开(公告)号：US20190300936A1

公开(公告)日：2019-10-03

申请号：US16382294

申请日：2019-04-12

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jacob K. FREUDENTHAL ,  Geoffrey DAHLHOFF ,  Kevin MAHER ,  Ming Song CHEN ,  Gary LIM ,  Ronald DANEHY ,  David FORTESCUE ,  Ming SHEN ,  Woon Liang Soh ,  Francis T. CHENG ,  Ruoyun WU ,  Thiam Chye LEE ,  Gary A. CHAPPELL ,  Chee Kiong LIM ,  Jeff DERE ,  Ted E. STRAUB ,  Jorge FONSECA ,  Kuan Moon BOO ,  Soo Yong LAU

IPC: C12Q1/686 ,  B01L3/00 ,  B01L7/00

Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lends can be a bi-convex lens.

公开(公告)号：US20180056296A1

公开(公告)日：2018-03-01

申请号：US15640241

申请日：2017-06-30

Applicant: Life Technologies Corporation

Inventor： Hon Siu SHIN ,  Chin Yong KOO ,  Way Xuang LEE ,  Chee Kiong LIM ,  Chee Wee CHING ,  Niroshan RAMACHANDRAN

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.

公开(公告)号：US20160214110A1

公开(公告)日：2016-07-28

申请号：US14917400

申请日：2014-09-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Hon Siu SHIN ,  Chin Yong KOO ,  Way Xuang LEE ,  Chee Kiong LIM ,  Chee Wee CHING ,  Niroshan RAMACHANDRAN

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.

Abstract translation: 公开了一种包括样品块和两个或更多个热电装置的热块组件。 样品块具有构造成容纳多个反应容器和相对的底表面的顶表面。 热电装置可操作地耦合到样品块，其中每个热电装置包括用于热传感器的壳体和具有控制器的热控制界面。 每个热电装置进一步构造成彼此独立地操作以在整个样品块中提供基本均匀的温度分布。