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1.发明申请HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME 有权混合聚合物，药物组合物及其合成方法公开(公告)号：US20150044189A1
公开(公告)日：2015-02-12
申请号：US14282228
申请日：2014-05-20
申请人： Kent Kirshenbaum , Paul Levine , Timothy Craven
发明人： Kent Kirshenbaum , Paul Levine , Timothy Craven
IPC分类号： C12N9/96
CPC分类号： C12N9/96 , A61K38/00 , C07K1/026 , C07K1/13 , C07K5/0806 , C07K5/081 , C07K7/06 , C07K7/08 , C12N9/22
摘要： Novel hybrid polymers are disclosed that have a structure represented by the following wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described.
摘要翻译： 公开了具有以下表示的结构的新型杂化聚合物，其中非生物低聚物，多肽，X，Y和R 1如本文所述。 还描述了通过新的恶唑烷基化合物制备杂化聚合物的方法。
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2.发明申请HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME 有权混合聚合物，药物组合物及其合成方法公开(公告)号：US20170015991A1
公开(公告)日：2017-01-19
申请号：US15281202
申请日：2016-09-30
申请人： Kent Kirshenbaum , Paul Levine , Timothy Craven
发明人： Kent Kirshenbaum , Paul Levine , Timothy Craven
摘要： Novel hybrid polymers are disclosed that have a structure represented by the following formula I: wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described.
摘要翻译： 其中非生物低聚物，多肽，X，Y和R1如本文所述。 还描述了通过新的恶唑烷基化合物制备杂化聚合物的方法。
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公开(公告)号：US09969773B2
公开(公告)日：2018-05-15
申请号：US14688026
申请日：2015-04-16
申请人： Kent Kirshenbaum , Paul Levine , Timothy Craven
发明人： Kent Kirshenbaum , Paul Levine , Timothy Craven
CPC分类号： C07K7/06 , C07K5/06165 , C07K5/0823 , C07K5/1024 , C07K7/08 , C07K14/001 , C07K17/08
摘要： Novel methods to prepare novel polymers are disclosed. Oxazolidinyl compounds according to formula IV: are also disclosed as intermediate compounds that can be reacted with an acid to form a polymer of formula I.
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4.发明申请公开(公告)号：US20180051056A1
公开(公告)日：2018-02-22
申请号：US15678204
申请日：2017-08-16
申请人： Kent Kirshenbaum , Timothy Craven
发明人： Kent Kirshenbaum , Timothy Craven
IPC分类号： C07K7/08
CPC分类号： C07K7/08 , C07K2319/70
摘要： Synthetic miniature protein scaffolds are described herein, as are compositions comprising same. Methods for the preparation of the synthetic miniature protein scaffolds and compositions thereof, and their use in preventing and/or treating conditions relating to diseases or disorders related to or associated with protein-protein interactions directly mediated by poly-proline type-II helix and/or beta-strand interactions are also encompassed herein.
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5.发明授权Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same 有权杂化聚合物，药物组合物及其合成方法公开(公告)号：US09458449B2
公开(公告)日：2016-10-04
申请号：US14282228
申请日：2014-05-20
申请人： Kent Kirshenbaum , Paul Levine , Timothy Craven
发明人： Kent Kirshenbaum , Paul Levine , Timothy Craven
CPC分类号： C12N9/96 , A61K38/00 , C07K1/026 , C07K1/13 , C07K5/0806 , C07K5/081 , C07K7/06 , C07K7/08 , C12N9/22
摘要： Novel hybrid polymers are disclosed that have a structure represented by the following wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described.
摘要翻译： 公开了具有以下表示的结构的新型杂化聚合物，其中非生物低聚物，多肽，X，Y和R 1如本文所述。 还描述了通过新的恶唑烷基化合物制备杂化聚合物的方法。
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6.发明申请NOVEL POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME 有权新型聚合物，药物组合物及其合成方法公开(公告)号：US20150299254A1
公开(公告)日：2015-10-22
申请号：US14688026
申请日：2015-04-16
申请人： Kent Kirshenbaum , Paul Levine , Timothy Craven
发明人： Kent Kirshenbaum , Paul Levine , Timothy Craven
CPC分类号： C07K7/06 , C07K5/06165 , C07K5/0823 , C07K5/1024 , C07K7/08 , C07K14/001 , C07K17/08
摘要： Novel methods to prepare novel polymers are disclosed. Oxazolidinyl compounds according to formula IV: are also disclosed as intermediate compounds that can be reacted with an acid to form a polymer of formula I.
摘要翻译： 公开了制备新型聚合物的新方法。 还公开了根据式IV的恶唑烷基化合物：作为可与酸反应以形成式I的聚合物的中间体化合物。
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