公开(公告)号：US20220170110A1

公开(公告)日：2022-06-02

申请号：US17601332

申请日：2019-11-19

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Daeyoup LEE ,  Taemook KIM ,  Sungwook HAN

IPC: C12Q1/6886

Abstract: The present invention relates to a cancer diagnostic marker screened using assay for transposase-accessible chromatin using sequencing (ATAC sequencing), and the use thereof. The open chromatin structural variation marker according to the present invention is useful as a cancer diagnostic marker because it can confirm the structural variation of chromatin with high accuracy. In addition, the open chromatin structural variation marker may be used as a new cancer diagnostic marker when detecting chromatin structural variation using a composition for detecting the marker.