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公开(公告)号：US12188063B2
公开(公告)日：2025-01-07
申请号：US17428477
申请日：2020-01-23
Applicant: INSTITUTE OF SCIENCE TOKYO
Inventor： Hiroshi Ueda , Jiulong Su , Tetsuya Kitaguchi , Yuki Ohmuro
Abstract: Provided as a mutant of β glucuronidase suitable for homogeneous immunoassays is a β glucuronidase mutant, wherein, in the amino acid sequence of Escherichia coli β glucuronidase, methionine at position 516 is substituted with lysine, and tyrosine at position 517 is unsubstituted or substituted with a non-tyrosine aromatic amino acid.
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