公开(公告)号：US20180230233A1

公开(公告)日：2018-08-16

申请号：US15893238

申请日：2018-02-09

Applicant: Genentech, Inc.

Inventor： Xiaocheng CHEN ,  Mark DENNIS ,  Janet JACKMAN ,  James T. KOERBER ,  Mason LU ,  Henry R. MAUN ,  Kathila RAJAPAKSA ,  Saroja RAMANUJAN ,  Tracy STATON ,  Lawren WU ,  Tangsheng YI

IPC: C07K16/40 ,  A61K39/395 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K47/10 ,  A61K45/06 ,  C07K16/24

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US20250002609A1

公开(公告)日：2025-01-02

申请号：US18740409

申请日：2024-06-11

Applicant: Genentech, Inc.

Inventor： Cecilia P.C. CHIU ,  Hilda Y. HERNANDEZ-BARRY ,  David B. IAEA ,  Moulay Hicham ALAOUI-ISMAILI ,  James T. KOERBER ,  Wei Yu LIN ,  Kelly LOYET ,  Yonglian SUN ,  Benjamin T. WALTERS ,  Jawahar SUDHAMSU

IPC: C07K16/40 ,  A61K47/68

Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.

公开(公告)号：US20230399417A1

公开(公告)日：2023-12-14

申请号：US18301169

申请日：2023-04-14

Applicant: Genentech, Inc.

Inventor： Christopher W. DAVIES ,  Nobuhiko KAYAGAKI ,  James T. KOERBER

IPC: C07K16/40 ,  C12N15/10

CPC classification number: C07K16/40 ,  C12N15/1044 ,  C07K2317/565

Abstract: Provided herein are antibodies that bind to cleaved inflammatory caspase (iCaspase) substrates and methods of screening for such antibodies. Also provided herein are detection methods using such antibodies for detecting a cleaved iCaspase substrate.

公开(公告)号：US20200325248A1

公开(公告)日：2020-10-15

申请号：US16916822

申请日：2020-06-30

Applicant: Genentech, Inc.

Inventor： Xiaocheng CHEN ,  Mark DENNIS ,  Janet JACKMAN ,  James T. KOERBER ,  Mason LU ,  Henry R. MAUN ,  Kathila RAJAPAKSA ,  Saroja RAMANUJAN ,  Tracy STATON ,  Lawren WU ,  Tangsheng YI

IPC: C07K16/40 ,  A61K39/395 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K47/10 ,  A61K45/06 ,  C07K16/24

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.

公开(公告)号：US20190367637A1

公开(公告)日：2019-12-05

申请号：US16544421

申请日：2019-08-19

Applicant: Genentech, Inc.

Inventor： Xiaocheng CHEN ,  Mark DENNIS ,  Janet JACKMAN ,  James T. KOERBER ,  Mason LU ,  Henry R. MAUN ,  Kathila RAJAPAKSA ,  Saroja RAMANUJAN ,  Tracy STATON ,  Lawren WU ,  Tangsheng YI

IPC: C07K16/40 ,  A61K39/395 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K47/10 ,  A61K45/06 ,  C07K16/24

Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.