公开(公告)号：US11466247B2

公开(公告)日：2022-10-11

申请号：US16648771

申请日：2018-09-17

申请人： Evogene Ltd. ,  Marrone Bio Innovations, Inc.

发明人： Or Rotem ,  Pamela G. Marrone ,  Sharon Ayal ,  Amit Vasavada ,  Brittany Pierce ,  Lisa N. Meihls ,  Vaka S. Reddy ,  Debora Wilk ,  Ana-Lucia Cordova-Kreylos ,  James Presnail ,  Eyal Emmanuel

IPC分类号： C12N1/20 ,  A01N63/28 ,  A01N63/20 ,  A01N63/23 ,  A01N63/22 ,  C07K14/195 ,  C07K14/32 ,  C07K14/36 ,  C12N15/01 ,  C12N15/82 ,  A01N63/50 ,  C12R1/01 ,  C12R1/07 ,  C12R1/125 ,  C12R1/465

摘要： Provided are biologically pure bacterial isolates characterized by a genome structure at least 90% similar to a genome structure of a bacterial species selected from the group consisting of: Streptomyces sp. E128 having an NRRL Accession No. B-67462, Bacillus amyloliquefaciens A190 having an NRRL Accession No. B-67464, Bacillus subtilis P243 having an NRRL Accession No. B-67459, Bacillus thuringiensis M979 having an NRRL Accession No. B-67457, Massilia aurea P63 having an NRRL Accession No. B-67461, Rhodococcus sp. G706, Stenotrophomonas maltophilia E132 having an NRRL Accession No. B-67460, Streptomyces aurantiacus A918, Streptomyces badius O180, Streptomyces mirabilis B670 having an NRRL Accession No. B67463, Streptomyces scopuliridis F427 having an NRRL Accession No. B-67458, and Streptomyces sp. L219. Also provided are whole cell broth or lysates thereof, and polynucleotide, polypeptides and constructs expressing same, compositions-of-matter comprising same and methods using same for killing or inhibiting the development of insects.

公开(公告)号：US20230115696A1

公开(公告)日：2023-04-13

申请号：US17929678

申请日：2022-09-02

申请人： Evogene Ltd. ,  Marrone Bio Innovations, Inc.

发明人： Or Rotem ,  Pamela G. Marrone ,  Sharon Ayal ,  Amit Vasavada ,  Brittany Pierce ,  Lisa N. Meihls ,  Vaka S. Reddy ,  Debora Wilk ,  Ana-Lucia Cordova-Kreylos ,  James Presnail ,  Eyal Emmanuel

IPC分类号： C12N1/20 ,  A01N63/28 ,  A01N63/20 ,  A01N63/23 ,  A01N63/22 ,  C07K14/195 ,  C07K14/32 ,  C07K14/36 ,  C12N15/01 ,  C12N15/82 ,  A01N63/50

摘要： Provided are biologically pure bacterial isolates characterized by a genome structure at least 90% similar to a genome structure of a bacterial species selected from the group consisting of: Streptomyces sp. E128 having an NRRL Accession No. B-67462, Bacillus amyloliquefaciens A190 having an NRRL Accession No. B-67464, Bacillus subtilis P243 having an NRRL Accession No. B-67459, Bacillus thuringiensis M979 having an NRRL Accession No. B-67457, Massilia aurea P63 having an NRRL Accession No. B-67461, Rhodococcus sp. G706, Stenotrophomonas maltophilia E132 having an NRRL Accession No. B-67460, Streptomyces aurantiacus A918, Streptomyces badius 0180, Streptomyces mirabilis B670 having an NRRL Accession No. B67463, Streptomyces scopuliridis F427 having an NRRL Accession No. B-67458, and Streptomyces sp. L219. Also provided are whole cell broth or lysates thereof, and polynucleotide, polypeptides and constructs expressing same, compositions-of-matter comprising same and methods using same for killing or inhibiting the development of insects.

公开(公告)号：US10995341B2

公开(公告)日：2021-05-04

申请号：US16218559

申请日：2018-12-13

申请人： Evogene Ltd.

发明人： Gil Ronen ,  Hagai Karchi ,  Alex Diber ,  Basia Judith Vinocur ,  Sharon Ayal ,  Eyal Emmanuel ,  Michael Gang ,  Dotan Dimet

IPC分类号： C12N15/82 ,  C07K14/415 ,  A01H1/00 ,  A01H5/00 ,  C12N15/00

摘要： Provided are methods of increasing tolerance of a plant to abiotic stress, and/or increasing biomass, growth rate, vigor and/or yield of a plant. The methods are effected by expressing within the plant an exogenous polynucleotide encoding a polypeptide comprising an amino acid sequence at least 90% homologous to the amino acid sequence selected from the group consisting of SEQ ID NOs:201, 207, 212, 202-206, 208-211, 213-391, 1655, 961-1529, and 1660-1663. Also provided are polynucleotides, nucleic acid constructs, polypeptides and transgenic plants expressing same which can be used to increase tolerance of a plant to abiotic stress, and/or increase biomass, growth rate, vigor and/or yield of a plant.

公开(公告)号：US10689662B2

公开(公告)日：2020-06-23

申请号：US15860780

申请日：2018-01-03

申请人： Evogene Ltd.

发明人： Eyal Emmanuel ,  Hagai Karchi

IPC分类号： C12N15/82 ,  C07K14/415

摘要： Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to SEQ ID NO: 321, 1-320, 322-480, 793-2945 or 2946; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to SEQ ID NO: 517, 481-516, 518-792, 2947-4662 or 4663, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogen use efficiency of a plant.

公开(公告)号：US20140289900A1

公开(公告)日：2014-09-25

申请号：US14239787

申请日：2012-08-23

申请人： EVOGENE LTD.

发明人： Limor Poraty-Gavra ,  Eyal Emmanuel ,  Hagai Karchi

IPC分类号： C12N15/82

CPC分类号： C12N15/8271 ,  C12N15/8247 ,  C12N15/8261 ,  C12Q1/6895 ,  C12Q2600/158 ,  Y02A40/146

摘要： Provided are isolated polynucleotides at least 80% identical to SEQ ID NOs: 1-479, 813-5173, 8511, 8513, 8515, 8517, 8519, 8521, 8523, 9096-9141 and 9142; and isolated polypeptides at least 80% homologous to an amino acid sequence selected from the group consisting of SEQ ID NOs: 624, 480-623, 625-812, 5174-7015, 7017-7021, 7024, 7026-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, 9143-9177, such as the polypeptides set forth in SEQ ID NO:480-812, 5174-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, and 9143-9177, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency, and/or abiotic stress tolerance of a plant.

摘要翻译： 提供与SEQ ID NO：1-479,813-5173,8511,8513,8515,8517,8519,8521,8523,9096-9141和9142至少80％相同的分离的多核苷酸; 和与选自SEQ ID NO：624,480-623,625-812,5174-7015,7017-7021,7024,7026-8510,8512,8514的氨基酸序列至少80％同源的分离多肽 ，8516,8518,8520,8522,8524,9143-9177，例如SEQ ID NO：480-812,574-8510,8512,8514,8516,8518,8520,8522,8524,9143中所示的多肽 -9177，包含其的核酸构建体，表达相同的转基因细胞和植物，以及用于其增加产量，生物量，生长速率，活力，油含量，纤维产量，纤维质量，氮利用效率和/或非生物胁迫耐受性的方法 的植物。

公开(公告)号：US20240102043A1

公开(公告)日：2024-03-28

申请号：US18360543

申请日：2023-07-27

申请人： Evogene Ltd.

发明人： Tidhar Turgeman ,  Ada Viterbo-Fainzilber ,  Eyal Emmanuel

IPC分类号： C12N15/82 ,  A01N63/50 ,  C07K14/415

CPC分类号： C12N15/8282 ,  A01N63/50 ,  C07K14/415 ,  C12N15/8216

摘要： The present invention relates to polynucleotides and polypeptides derived from plants and bacteria which are associated with increased resistance of plants to pathogenic fungi and/or Oomycetes. The fungicidal polypeptides of the invention are particularly effective in combating fungi inducing root rot and stalk rot in plants. The present invention further provides methods of using the polynucleotides and polypeptides of the invention for controlling plant fungal/Oomycetes pathogens and for producing transgenic plants having increased resistance to the pathogens.

公开(公告)号：US11542522B2

公开(公告)日：2023-01-03

申请号：US16847776

申请日：2020-04-14

申请人： Evogene Ltd.

发明人： Eyal Emmanuel ,  Hagai Karchi

IPC分类号： C12N15/82 ,  C07K14/415

摘要： Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to SEQ ID NO: 321, 1-320, 322-480, 793-2945 or 2946; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to SEQ ID NO: 517, 481-516, 518-792, 2947-4662 or 4663, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, abiotic stress tolerance, and/or nitrogen use efficiency of a plant.

公开(公告)号：US10975382B2

公开(公告)日：2021-04-13

申请号：US16037055

申请日：2018-07-17

申请人： Evogene Ltd.

发明人： Sharon Ayal ,  Eyal Emmanuel ,  Zur Granevitze ,  Alex Diber ,  Basia Judith Vinocur ,  Hagai Karchi ,  Yoav Herschkovitz

IPC分类号： C12N15/82 ,  C07K14/415

摘要： Provided are isolated polynucleotides comprising a nucleic acid sequence at least 80% identical to SEQ ID NO:619, 617, 606, 615, 629, 1-36, 40, 41, 43-45, 49, 52-56, 58, 113-343, 351, 354-358, 605, 607-614, 616, 618, 620-628, 630-638, 642, 645, 650, 651, 670, or 671. Also provided are nucleic acid constructs comprising same, isolated polypeptides encoded thereby, transgenic cells and transgenic plants comprising same and methods of using same for increasing abiotic stress tolerance, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, and/or nitrogen use efficiency of a plant.

公开(公告)号：US20180245094A1

公开(公告)日：2018-08-30

申请号：US15979507

申请日：2018-05-15

申请人： Evogene Ltd.

发明人： Limor Poraty-Gavra ,  Eyal Emmanuel ,  Hagai Karchi

IPC分类号： C12N15/82 ,  C12Q1/6895

CPC分类号： C12N15/8261 ,  C12Q1/6895 ,  C12Q2600/158 ,  Y02A40/146

摘要： Provided are isolated polynucleotides at least 80% identical to SEQ ID NOs: 1-479, 813-5173, 8511, 8513, 8515, 8517, 8519, 8521, 8523, 9096-9141 and 9142; and isolated polypeptides at least 80% homologous to an amino acid sequence selected from the group consisting of SEQ ID NOs: 624, 480-623, 625-812, 5174-7015, 7017-7021, 7024, 7026-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, 9143-9177, such as the polypeptides set forth in SEQ ID NO:480-812, 5174-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, and 9143-9177, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency, and/or abiotic stress tolerance of a plant.

公开(公告)号：US09783818B2

公开(公告)日：2017-10-10

申请号：US14636275

申请日：2015-03-03

申请人： Evogene Ltd.

发明人： Basia Judith Vinocur ,  Sharon Ayal ,  Alex Diber ,  Eyal Emmanuel ,  Gil Ronen ,  Michael Gang ,  Dotan Dimet ,  Hagai Karchi ,  Yoav Herschkovitz

IPC分类号： C12N15/82 ,  C07K14/415

CPC分类号： C12N15/8261 ,  C07K14/415 ,  C12N15/8247 ,  C12N15/8269 ,  C12N15/8271 ,  C12N15/8273 ,  Y02A40/146

摘要： Provided are methods of increasing nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant by expressing within the plant an exogenous polynucleotide comprising a nucleic acid sequence encoding a polypeptide at least 80% identical to SEQ ID NO: 2560, 2557, 184, 238, 188, 154-156, 158-161, 163-183, 185-187, 189-197, 200-237, 239-264, 266-269, 1351, 1365-1425, 1429-1457, 1459, 1461-1730, 1735, 1739-2397, 2533-2541, 2544-2556, 2558, 2559, 2561-2562 or 2563. Also provided are isolated polynucleotides and polypeptides which can be used to increase nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress tolerance of a plant of a plant.