公开(公告)号：US10830733B2

公开(公告)日：2020-11-10

申请号：US15870565

申请日：2018-01-12

Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE

Inventor： Hyo-Bong Hong ,  Jae Chan Jeong ,  Seung-Min Choi ,  Chang-Beom Kim

IPC: G01N27/72 ,  G01N33/02 ,  G01N33/10 ,  G01N27/90 ,  G01N27/82

Abstract: Disclosed herein are a method and apparatus for scanning a multilayer material using magnetism. The apparatus for scanning a multilayer material includes at least one measurement head for exciting a mixed magnetic field on a multilayer specimen using at least one excitation solenoid coil and detecting detection signals from the multilayer specimen using a detection solenoid coil, a movement controller for moving any one of the at least one measurement head and a stage on which the multilayer specimen is placed in order to detect detection signals for all parts of the multilayer specimen, and a signal controller for generating two excitation signals having different frequencies in order to generate the mixed magnetic field and for generating a scanning result for the multilayer specimen by collecting the detection signals.

公开(公告)号：US10139214B2

公开(公告)日：2018-11-27

申请号：US15183639

申请日：2016-06-15

Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE

Inventor： Hyo-Bong Hong ,  Seung-Min Choi ,  Chang-Beom Kim

IPC: G01B7/004

Abstract: Disclosed herein are an apparatus for acquiring the location coordinates of an object to be measured using two measurement heads and a method using the apparatus. The apparatus for acquiring the location coordinates of an object includes two measurement heads for individually detecting a signal corresponding to the object to be measured, a measurement head fixing unit for placing the two measurement heads so as to face each other with the object therebetween, a rotatable structure for rotating the measurement head fixing unit, and a location determination unit for acquiring the location coordinates of the object to be measured based on the strengths of the two detection signals detected by the measurement heads.

公开(公告)号：US09541561B2

公开(公告)日：2017-01-10

申请号：US13843574

申请日：2013-03-15

Applicant: Electronics and Telecommunications Research Institute

Inventor： Chang-Beom Kim ,  Kibong Song ,  Kwan Su Kim

IPC: G01N33/543 ,  G01N33/68

CPC classification number: G01N33/6896 ,  G01N33/54326 ,  G01N33/54373

Abstract: Provided is a method for diagnosing Alzheimer/s disease using a decomposed biomaterial. The method includes: preparing magnetic particles on which primary capture antibodies specifically bound to beta-amyloid are adsorbed; decomposing a biomaterial including beta-amyloid; binding the beta-amyloid to the primary capture antibodies; binding secondary capture antibodies labeled with a fluorescent material to the magnetic particles bound to the beta-amyloid to form a complex; disposing the complex in a channel region of a photo field effect transistor in which a photocurrent is changed according to the amount of incident light; and measuring the photocurrent changed by light excited from the complex to quantify the concentration of the beta-amyloid existing in the biomaterial.

Abstract translation: 提供了使用分解生物材料诊断阿尔茨海默病的方法。 该方法包括：制备其上吸附了特异性结合β-淀粉样蛋白的初级捕获抗体的磁性颗粒; 分解包括β-淀粉样蛋白在内的生物材料; 将β-淀粉样蛋白与初级捕获抗体结合; 用荧光材料标记的结合二次捕获抗体结合到β-淀粉样蛋白上形成复合物的磁性颗粒; 将复合物设置在光电流根据入射光量变化的光电场效应晶体管的沟道区域中; 并测量由络合物激发的光改变的光电流，以量化存在于生物材料中的β-淀粉样蛋白的浓度。

公开(公告)号：US11480634B2

公开(公告)日：2022-10-25

申请号：US17318753

申请日：2021-05-12

Applicant: Electronics and Telecommunications Research Institute

Inventor： Eul-Gyoon Lim ,  Jin-Sun Kim ,  Chang-Beom Kim ,  Jae-Chan Jong ,  Seung-Min Choi ,  Hyo-Bong Hong

IPC: G01R33/12 ,  A61B5/0515 ,  G01B21/22

Abstract: Disclosed herein is a nano-magnetic-particle-imaging apparatus, including a measurement head including excitation and detection coils and accommodating a sample bed for a sample including nano magnetic particles; a gradient magnetic field generation unit for generating a magnetic field having a strength equal to or greater than that of the saturation magnetic field of the nano magnetic particles in a spacing area between identical magnetic poles facing each other and forming a field-free region in a portion thereof; a first driving unit for linearly moving the sample bed; a second driving unit for rotating the gradient magnetic field generation unit in a plane; a third driving unit for linearly reciprocating the gradient magnetic field generation unit; and a control unit for applying a signal to the excitation coil, controlling the driving units, and imaging 3D distribution of the nano magnetic particles based on a detection signal output from the detection coil.

公开(公告)号：US10948556B2

公开(公告)日：2021-03-16

申请号：US16205044

申请日：2018-11-29

Applicant: Electronics and Telecommunications Research Institute

Inventor： Hyo-Bong Hong ,  Jae-Chan Jeong ,  Seung-Min Choi ,  Chang-Beom Kim

IPC: G01R33/36 ,  G01R33/48 ,  G01R33/381 ,  G01N27/72 ,  A61N2/00 ,  H05G1/60 ,  G01R33/12

Abstract: Disclosed herein are a method for modifying a magnetic field using magnetic nanoparticles and an apparatus therefor. The method for modifying a magnetic field includes applying current to a single solenoid coil or to two parallel solenoid coils, measuring a strength of a magnetic field generated by the current at a preset target location using a measurement sensor, and controlling the strength of the magnetic field based on a concentration of a magnetic nanoparticle sample mounted in the single solenoid coil or the two solenoid coils so that the strength of the magnetic field matches a preset target value.