A method and apparatus for controlling interference in a wireless communication system are disclosed. A method for measuring inter-cell interference by a pico eNB in a wireless communication system includes: receiving transmission information of a dummy signal to be transmitted on at least one candidate carrier from a neighbor pico eNB; scheduling at least one user equipment (UE) served by the pico eNB to measure the dummy signal based on the transmission information; receiving a measurement value of the dummy signal from the at least one UE; and transmitting a measurement report of the dummy signal based on the measurement value to the neighbor pico eNB, wherein the dummy signal transmission information is specified for each of a plurality of subframe sets of the at least one candidate carrier.