Invention Grant
- Patent Title: Exosome analysis method, exosome analysis apparatus, antibody-exosome complex, and exosome electrophoresis chip
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Application No.: US14629028Application Date: 2015-02-23
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Publication No.: US09952215B2Publication Date: 2018-04-24
- Inventor: Takanori Ichiki , Takanori Akagi , Hirofumi Shiono
- Applicant: The University of Tokyo , NIKON CORPORATION
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: The University of Tokyo,Nikon Corporation
- Current Assignee: The University of Tokyo,Nikon Corporation
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2012-185666 20120824
- Main IPC: G01N27/447
- IPC: G01N27/447 ; G01N33/566 ; G01N33/574 ; G01N33/543 ; G01N33/561
Abstract:
A method of analyzing an exosome is provided for detecting abnormality in a cell, including: (a) a step of preparing an exosome from a sample; (b) a step of bringing the exosome prepared in the step (a) into contact with a first antibody to a protein which exists on the surface of the exosome as an antigen and forming a first antibody-exosome complex; and (c) a step of measuring a zeta potential of the first antibody-exosome complex.
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