- 专利标题: Ultra-rapid tissue cryopreservation method and apparatus
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申请号: US15128174申请日: 2015-03-27
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公开(公告)号: US09936690B2公开(公告)日: 2018-04-10
- 发明人: James Dale Benson
- 申请人: BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY
- 申请人地址: US IL Dekalb
- 专利权人: BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY
- 当前专利权人: BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY
- 当前专利权人地址: US IL Dekalb
- 代理机构: Barnes & Thornburg LLP
- 代理商 Alice O. Martin
- 国际申请: PCT/US2015/023014 WO 20150327
- 国际公布: WO2015/148935 WO 20151001
- 主分类号: A01N1/00
- IPC分类号: A01N1/00 ; A01N1/02
摘要:
A method and apparatus for the processing of tissue and cellular material during cryopreservation and/or processing for microscopy. The method and apparatus maximizes heat transfer coefficients by using liquid-free cryopreservation protocols and maximizing glass transition characteristics through increasing pressure during cryopreservation. Cooling rates combined with megapascal pressures reduced the required concentration of cryoprotective agents (CPAs) needed for ice-free cell and tissue cryopreservation.
公开/授权文献
- US20170094962A1 ULTRA-RAPID TISSUE CRYOPRESERVATION METHOD AND APPARATUS 公开/授权日:2017-04-06
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