- 专利标题： Method of selectively inhibiting Ras-mediated tumor growth in humans
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申请号： US15056202申请日： 2016-02-29
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公开(公告)号： US09931315B2公开(公告)日： 2018-04-03
- 发明人: Gary A. Piazza , Xi Chen , Adam B. Keeton , Michael R. Boyd
- 申请人： ADT PHARMACEUTICALS, INC.
- 申请人地址： US AL Orange Beach
- 专利权人： ADT Pharmaceuticals, Inc.
- 当前专利权人： ADT Pharmaceuticals, Inc.
- 当前专利权人地址： US AL Orange Beach
- 代理机构： Goodwin Procter LLP
- 主分类号： A61K31/341
- IPC分类号： A61K31/341 ; C07D307/52 ; C07C235/34 ; C07D213/75 ; C07D207/14 ; C07D213/40 ; C07D207/335 ; C07C311/29 ; A61K31/165 ; A61K31/216 ; A61K31/401 ; A61K31/421 ; A61K31/4402 ; A61K31/4406 ; A61K31/496 ; A61K31/5375 ; A61K31/5377 ; A61K31/167 ; A61K31/40 ; A61K45/06 ; G01N33/574
摘要：
Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene.
公开/授权文献
- US20160175275A1 METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES 公开/授权日：2016-06-23
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