A system that incorporates the subject disclosure may include, for example, determining an interference based on a channel gain for each signal of a group of signals received at a receiver from a group of transmitters. A determination is made as to whether the interference satisfies a threshold range of an analog-to-digital converter of the receiver for each of the group of transmitters. An analog time domain cancellation is performed responsive to a determination that the interference does not satisfy the threshold range, and a digital time domain cancellation is performed responsive to a determination that the interference satisfies the threshold range. Other embodiments are disclosed.