Invention Grant
- Patent Title: Particle and contrast agent having the particle
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Application No.: US13817711Application Date: 2011-08-23
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Publication No.: US09610367B2Publication Date: 2017-04-04
- Inventor: Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
- Applicant: Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2010-187667 20100824; JP2011-086280 20110408
- International Application: PCT/JP2011/069370 WO 20110823
- International Announcement: WO2012/026608 WO 20120301
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K49/00 ; A61K9/51 ; A61K49/22 ; B82Y15/00 ; B82Y30/00

Abstract:
There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.
Public/Granted literature
- US20130209367A1 PARTICLE AND CONTRAST AGENT HAVING THE PARTICLE Public/Granted day:2013-08-15
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