发明授权
US09586968B2 Bicycloamine-substituted-N-benzenesulfonamide compounds with selective activity in voltage-gated sodium channels 有权
在电压门控钠通道中具有选择性活性的双环胺取代的N-苯磺酰胺化合物

Bicycloamine-substituted-N-benzenesulfonamide compounds with selective activity in voltage-gated sodium channels
摘要:
Disclosed are compounds of Formula A-a, or a salt thereof: Where “B1” and “R1” through “R5” are as defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A-a or their salts, and methods of treating neuropathic pain disorders using the same.
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