Invention Grant
- Patent Title: Lipids and compositions for intracellular delivery of biologically active compounds
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Application No.: US14178538Application Date: 2014-02-12
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Publication No.: US09433681B2Publication Date: 2016-09-06
- Inventor: Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
- Applicant: AXOLABS GMBH
- Applicant Address: DE Kulmbach
- Assignee: AXOLABS GMBH
- Current Assignee: AXOLABS GMBH
- Current Assignee Address: DE Kulmbach
- Agency: Medler Ferro Woodhouse & Mills PLLC
- Priority: EP11166353 20110517
- Main IPC: C07C211/22
- IPC: C07C211/22 ; C07D295/30 ; C07D241/04 ; A61K31/713 ; A61K31/7088 ; C07C211/11 ; C07C211/13 ; A61K47/18 ; A61K31/575 ; A61K31/70 ; B82Y5/00 ; C07C217/42 ; C07C211/14 ; C07C217/08 ; C07C217/28 ; A61K9/127 ; A61K9/14 ; A61K38/02 ; A61K47/22 ; A61K39/00
Abstract:
The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
Public/Granted literature
- US20140162962A1 NOVEL LIPIDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE COMPOUNDS Public/Granted day:2014-06-12
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