Invention Grant
- Patent Title: Compositions and methods for treating cancer
- Patent Title (中): 用于治疗癌症的组合物和方法
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Application No.: US13979927Application Date: 2012-01-18
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Publication No.: US09402865B2Publication Date: 2016-08-02
- Inventor: Daniel J. Powell , George Coukos
- Applicant: Daniel J. Powell , George Coukos
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Kelly J. Morgan
- International Application: PCT/US2012/021738 WO 20120118
- International Announcement: WO2012/099973 WO 20120726
- Main IPC: A61K35/14
- IPC: A61K35/14 ; C07K16/28 ; C07K14/705 ; A61K35/17 ; A61K39/00 ; A61K39/395
Abstract:
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα) binding domain and 4-1BB (CD137) costimulatory domain to treat ovarian cancer.
Public/Granted literature
- US20140050708A1 Compositions and Methods for Treating Cancer Public/Granted day:2014-02-20
Information query
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