Transmit power (e.g., maximum transmit power) may be defined based on the maximum received signal strength allowed by a receiver and a total received signal strength from transmitting nodes at the receiver. Transmit power may be defined for an access node (e.g., a femto node) such that a corresponding outage created in a cell (e.g., a macro cell) is limited while still providing an acceptable level of coverage for access terminals associated with the access node. An access node may autonomously adjust its transmit power based on channel measurement and a defined coverage hole to mitigate interference and perform a self-calibration process.