A method for enabling inter-process communication between a first application and a second application, the first application running within a first context and the second application running within a second context of a virtualization system is described. The method includes receiving a request to attach a shared region of memory to a memory allocation, identifying a list of one or more physical memory pages defining the shared region that corresponds to the handle, and mapping guest memory pages corresponding to the allocation to the physical memory pages. The request is received by a framework from the second application and includes a handle that uniquely identifies the shared region of memory as well as an identification of at least one guest memory page corresponding to the memory allocation. The framework is a component of a virtualization software, which executes in a context distinct from the context of the first application.