发明授权
US09382553B2 Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound
有权
用于生产1-脱氧纤维素5-磷酸酯（DXP）和/或DXP衍生化合物的宿主细胞和方法
- 专利标题： Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound
- 专利标题（中）： 用于生产1-脱氧纤维素5-磷酸酯（DXP）和/或DXP衍生化合物的宿主细胞和方法
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申请号： US13587826申请日： 2012-08-16
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公开(公告)号： US09382553B2公开(公告)日： 2016-07-05
- 发明人: James Kirby , Jeffrey L. Fortman , Minobu Nishimoto , Jay D. Keasling
- 申请人： James Kirby , Jeffrey L. Fortman , Minobu Nishimoto , Jay D. Keasling
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Lawrence Berkeley National Laboratory
- 代理商 Robin C. Chiang
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C12N9/04 ; C12P19/02 ; C12P5/00
摘要：
The present invention provides for a genetically modified host cell capable of producing 1-deoxyxylulose 5-phosphate or 1-deoxy-D-xylulose 5-phosphate (DXP) (12), and optionally one or more DXP derived compounds, comprising: (a) a mutant RibB, or functional variant thereof, capable of catalyzing xylulose 5-phosphate and/or ribulose 5-phosphate to DXP, or (b) a YajO, or functional variant thereof, and a XylB, or functional variant thereof.
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