Invention Grant
- Patent Title: Tubulysin compounds, methods of making and use
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Application No.: US14605549Application Date: 2015-01-26
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Publication No.: US09382289B2Publication Date: 2016-07-05
- Inventor: Qiang Cong , Heng Cheng , Sanjeev Gangwar
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Yuan Chao
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K5/117 ; A61K47/48 ; C07K7/06 ; C07K5/10 ; A61K38/07 ; C07K5/06 ; C07K5/078 ; A61K38/05 ; C07K5/107
Abstract:
Tubulysin compounds of the formula (I) where R1, R2, R3a, R3b, R4, R5, W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
Public/Granted literature
- US20150132324A1 TUBULYSIN COMPOUNDS, METHODS OF MAKING AND USE Public/Granted day:2015-05-14
Information query
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