Invention Grant
- Patent Title: Substituted sulfonamides useful as antiapoptotic Bcl inhibitors
- Patent Title (中): 用作抗细胞凋亡Bcl抑制剂的取代磺酰胺
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Application No.: US14122173Application Date: 2012-05-23
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Publication No.: US09346795B2Publication Date: 2016-05-24
- Inventor: Robert M. Borzilleri , Zhen-Wei Cai , Andrew J. Tebben , Heidi L. Perez , Liping Zhang , Gretchen M. Schroeder , Donna D. Wei
- Applicant: Robert M. Borzilleri , Zhen-Wei Cai , Andrew J. Tebben , Heidi L. Perez , Liping Zhang , Gretchen M. Schroeder , Donna D. Wei
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary D. Greenblatt
- International Application: PCT/US2012/039094 WO 20120523
- International Announcement: WO2012/162365 WO 20121129
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/55 ; A61K31/54 ; A61K31/497 ; A61K31/535 ; C07D417/10 ; C07D413/10 ; C07D403/10 ; C07D401/10 ; C07D403/12 ; C07D403/14 ; C07D413/12
Abstract:
Disclosed are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and Q and G are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bcl-2 family antiapoptotic proteins for the treatment of cancer; and pharmaceutical compositions comprising such compounds.
Public/Granted literature
- US20140135318A1 SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS Public/Granted day:2014-05-15
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