发明授权
- 专利标题: Assays and kits for detecting protein binding
- 专利标题(中): 用于检测蛋白质结合的测定和试剂盒
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申请号: US11895307申请日: 2007-08-23
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公开(公告)号: US09267165B2公开(公告)日: 2016-02-23
- 发明人: David J. Lockhart , Patrick Parvis Zarrinkar , Daniel Kelly Treiber
- 申请人: David J. Lockhart , Patrick Parvis Zarrinkar , Daniel Kelly Treiber
- 申请人地址: US CA Fremont
- 专利权人: DiscoveRx Corporation
- 当前专利权人: DiscoveRx Corporation
- 当前专利权人地址: US CA Fremont
- 代理机构: Bozicevic, Field & Francis LLP
- 代理商 David J. Aston
- 主分类号: C12Q1/48
- IPC分类号: C12Q1/48 ; G01N33/566 ; G01N33/543 ; G01N33/577
摘要:
The invention provides methods for determining the interactions between phage-displayed proteins and test molecules. The phage-displayed proteins are contacted with a reference moiety in the presence and absence of a test molecule; the behavior of the phage-displayed proteins as a function of concentration of the test molecule permits calculation of the binding affinity of the phage-displayed protein for the test molecule.
公开/授权文献
- US20080058219A1 Assays and kits for detecting protein binding 公开/授权日:2008-03-06
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