发明授权
US09174941B2 Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
有权
吡唑基和嘧啶基三环烯酮作为抗氧化剂炎症调节剂
- 专利标题: Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators
- 专利标题(中): 吡唑基和嘧啶基三环烯酮作为抗氧化剂炎症调节剂
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申请号: US13939818申请日: 2013-07-11
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公开(公告)号: US09174941B2公开(公告)日: 2015-11-03
- 发明人: Eric Anderson , Gary L. Bolton , Bradley Caprathe , Xin Jiang , Chitase Lee , William H. Roark , Melean Visnick
- 申请人: REATA PHARMACEUTICALS, INC.
- 申请人地址: US TX Irving
- 专利权人: Reata Pharmaceuticals, Inc.
- 当前专利权人: Reata Pharmaceuticals, Inc.
- 当前专利权人地址: US TX Irving
- 代理机构: Parker Highlander PLLC
- 主分类号: C07D231/54
- IPC分类号: C07D231/54 ; C07D239/70 ; C07D401/04 ; C07D403/04 ; C07D413/04 ; C07D417/04 ; C07D487/04
摘要:
Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.
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