发明授权
- 专利标题: Dry composition of reaction compounds with stabilized polymerase
- 专利标题(中): 具有稳定聚合酶的反应化合物的干组合
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申请号: US14169993申请日: 2014-01-31
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公开(公告)号: US09163286B2公开(公告)日: 2015-10-20
- 发明人: Thomas Metzler , Tobias Haslinger , Annette Peceny , Harald Sobek
- 申请人: Roche Diagnostics Operations, Inc.
- 申请人地址: US IN Indianapolis
- 专利权人: Roche Diagnostics Operations, Inc.
- 当前专利权人: Roche Diagnostics Operations, Inc.
- 当前专利权人地址: US IN Indianapolis
- 代理机构: Faegre Baker Daniels LLP
- 优先权: EP08022082 20081219
- 主分类号: C12P19/34
- IPC分类号: C12P19/34 ; C12Q1/68 ; C12N9/12
摘要:
The present invention provides methods to obtain dry compositions of reaction compounds that maintain the biological activity of the compounds upon re-solubilization after a certain storage time. Preferably, the dry composition comprises a polymerase, and the dry composition is usable for polymerase chain reaction (PCR) amplification after re-solubilization.
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