发明授权
US09156777B2 Process for preparing N-acyl amino acid salts 有权
制备N-酰基氨基酸盐的方法

  • 专利标题: Process for preparing N-acyl amino acid salts
  • 专利标题(中): 制备N-酰基氨基酸盐的方法
  • 申请号: US14411971
    申请日: 2013-06-27
  • 公开(公告)号: US09156777B2
    公开(公告)日: 2015-10-13
  • 发明人: Bing WangGregory P Dado
  • 申请人: Stepan Company
  • 申请人地址: US IL Northfield
  • 专利权人: Stepan Company
  • 当前专利权人: Stepan Company
  • 当前专利权人地址: US IL Northfield
  • 代理机构: Dilworth IP LLC
  • 国际申请: PCT/US2013/048341 WO 20130627
  • 国际公布: WO2014/008103 WO 20140109
  • 主分类号: C07C233/91
  • IPC分类号: C07C233/91 C07C231/02 C07C231/10
Process for preparing N-acyl amino acid salts
摘要:
Improved processes for making an N-acyl amino acid salt from a fatty alkyl ester or a polyol ester are disclosed. Each process uses a polyol selected from glycerin or propylene glycol in an amount effective to keep the reaction mixture fluid until conversion to the N-acyl amino acid salt reaches the desired level of completion. In one process, a fatty alkyl ester reacts with an amino acid salt in the presence of glycerin or propylene glycol to produce an N-acyl amino acid salt. In another process, a polyol ester reacts with the amino acid salt in the presence of added glycerin or propylene glycol to produce the N-acyl amino acid salt. We surprisingly found that an effective amount of glycerin or propylene glycol minimizes or eliminates reaction mixture solidification or foaming, reduces color, and minimizes the level of di- and tripeptide by-products. In a related process, water is added when conversion of the amino acid salt to the N-acyl amino acid salt is in the range of 50 to 90 mole %. Water addition improves processability, advances conversion without producing excessive soap, and helps to ensure that the N-acyl amino acid salt will have low color and a small proportion of by-products.
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