发明授权
US09128014B2 High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
有权
基于数字微流体实验室芯片的高通量和体积误差弹性稀释
- 专利标题: High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
- 专利标题(中): 基于数字微流体实验室芯片的高通量和体积误差弹性稀释
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申请号: US13809328申请日: 2010-11-12
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公开(公告)号: US09128014B2公开(公告)日: 2015-09-08
- 发明人: Bhargab B. Bhattacharya , Sarmishtha Ghoshal , Sudip Roy , Krishnendu Chakrabarty
- 申请人: Bhargab B. Bhattacharya , Sarmishtha Ghoshal , Sudip Roy , Krishnendu Chakrabarty
- 申请人地址: IN Kolkata
- 专利权人: INDIAN STATISTICAL INSTITUTE
- 当前专利权人: INDIAN STATISTICAL INSTITUTE
- 当前专利权人地址: IN Kolkata
- 代理机构: Workman Nydegger
- 优先权: IN769/KOL/2010 20100715
- 国际申请: PCT/IB2010/002895 WO 20101112
- 国际公布: WO2012/007786 WO 20120119
- 主分类号: G01N1/38
- IPC分类号: G01N1/38 ; B01F13/00 ; B01F15/04 ; B01L3/00 ; B01F3/08
摘要:
Systems and methods are provided for producing fluids with desired concentration factors from the given supply of any two concentration factors, one greater than the target CF and one less than the target CF, of the same fluid. According to one embodiment, a method is provided that stores intermediate waste droplets from a sequence of mix and split steps and repeats certain steps of the sequence using the stored intermediate waste droplets. Such a method may produce additional target CF droplets faster than repeating the entire sequence. In another embodiment, a method of volumetric error resilient target CF droplet generation has been described, and includes reusing the stored intermediate waste droplets and involves a collection of capacitive sensing circuits associated with some electrode platforms.
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