A lever for a drive-by-wire system installed in a vehicle, may include a lever body that is rotatably mounted on a console surface of the vehicle, and an acceleration lever and a steering roller that are installed in the lever body, such that it is possible to control a change of a gear shift stage, acceleration, and a change of a proceeding direction of the vehicle in a unified manner, and there is no risk of erroneous manipulations of an accelerator pedal and a brake pedal, and acceleration and a proceeding direction may be changed using a finger, thereby improving performance in manipulating the vehicle.