A method and apparatus relate to coexistence of multiple RF subsystems on a communication device. An apparatus may include a plurality of radio frequency (RF) subsystems configured to receive or transmit communication signals; and an interference table indicative of zones of interference among the multiple RF subsystems, the zones of interference being based on RF measurements. At least one of the RF subsystems comprises a coexistence module configured to communicate coexistence-related messages with of the other RF subsystems, the coexistence-related messages being based on the zones of interference.