An electro-optical tissue stimulator for administering therapy to a body is disclosed comprising a housing and an active tip. The electro-optical tissue stimulator includes a microcurrent electrostimulation therapy unit which delivers current through a first and a second electrode in the active tip. The electro-optical tissue stimulator also includes an optical radiation therapy unit which delivers optical radiation through a light output port in the active tip. The active tip is shaped for administering myofascial tissue release therapy. The device can administer microcurrent electrostimulation therapy, optical radiation therapy, and myofascial tissue release therapy to tissues of a body. A method of treating pain is disclosed which includes the steps of identifying a treatment area on a body to receive therapy, and contacting the treatment area with the active tip, wherein the treatment area receives microcurrent electrostimulation therapy, optical radiation therapy, and myofascial tissue release therapy.