发明授权
US08962268B2 Method for determining survival prognosis of patients suffering from non-small cell lung cancer (NSCLC)
有权
确定患有非小细胞肺癌(NSCLC)患者生存预后的方法
- 专利标题: Method for determining survival prognosis of patients suffering from non-small cell lung cancer (NSCLC)
- 专利标题(中): 确定患有非小细胞肺癌(NSCLC)患者生存预后的方法
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申请号: US13138849申请日: 2010-04-12
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公开(公告)号: US08962268B2公开(公告)日: 2015-02-24
- 发明人: Richard De Wijn , Robby Ruijtenbeek , Maria Helena Hilhorst
- 申请人: Richard De Wijn , Robby Ruijtenbeek , Maria Helena Hilhorst
- 申请人地址: NL 's-Hertogenbosch
- 专利权人: Pamgene B.V.
- 当前专利权人: Pamgene B.V.
- 当前专利权人地址: NL 's-Hertogenbosch
- 代理机构: Amster, Rothstein & Ebenstein LLP
- 优先权: EP09157816 20090410
- 国际申请: PCT/EP2010/054763 WO 20100412
- 国际公布: WO2010/115997 WO 20101014
- 主分类号: G01N33/00
- IPC分类号: G01N33/00 ; C12Q1/48 ; G01N33/574 ; G01N33/48 ; C40B30/06 ; C40B30/08
摘要:
The present invention relates to a method for determining the survival prognosis of patients suffering from non-small cell lung cancer. More specifically, the present invention provides methods which measure kinase activity by studying phosphorylation levels in response to a kinase inhibitor and profiles in samples obtained from patients diagnosed with non-small cell lung cancer. The present invention also provides methods for predicting the response of a patient diagnosed with non-small cell lung cancer to a medicament.
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